ID A0A1B9ID58_9TREE Unreviewed; 987 AA.
AC A0A1B9ID58;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
GN ORFNames=I206_00541 {ECO:0000313|EMBL:OCF53240.1};
OS Kwoniella pini CBS 10737.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296096 {ECO:0000313|EMBL:OCF53240.1, ECO:0000313|Proteomes:UP000094020};
RN [1] {ECO:0000313|EMBL:OCF53240.1, ECO:0000313|Proteomes:UP000094020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10737 {ECO:0000313|EMBL:OCF53240.1,
RC ECO:0000313|Proteomes:UP000094020};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus pinus CBS10737.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000094020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10737 {ECO:0000313|Proteomes:UP000094020};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the post-replicative DNA mismatch repair system
CC (MMR). {ECO:0000256|RuleBase:RU003756}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|RuleBase:RU003756}.
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DR EMBL; KI894007; OCF53240.1; -; Genomic_DNA.
DR RefSeq; XP_019014459.1; XM_019152321.1.
DR AlphaFoldDB; A0A1B9ID58; -.
DR STRING; 1296096.A0A1B9ID58; -.
DR GeneID; 30168910; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000094020; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 3.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 3.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003756};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003756};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003756};
KW Reference proteome {ECO:0000313|Proteomes:UP000094020}.
FT DOMAIN 850..866
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 532..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..548
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 549..570
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 987 AA; 110346 MW; 3AB3AE3D24075786 CRC64;
MSASIDSAKT EETVLTPDAE LSELNKAIAT GVIPDSPLSR EVYINWLRFP DCILLTRVGK
FYESYFEPAR QLSSILNIKL AQKTYKLANT ETESKSTKSK SKTKETERKF PFAGFPVAAL
DKYLKILVQE LGHTVVIVEE YDEEGSIAYV GKKITAATGP KERRVYRVVT PGTMIDEGWL
DGNESRFLLA IAMNDQRAVV DGDATATLSL AYTDPSTGEF FTKDTFLSNM EDELARIAPR
EIVLDRSLRA AWQDDAGEPL RSDESSIPGL FKLLQVLGVH VSFADPSRPP PLWATGVLSP
DVSVRPQTTE NVAIALLRHH LQYALRESMP ALTQPNRQVA ESQMQIDAAT LQALEIRHAL
RPGGLVAIGE RQTISPVSSR GTLLSVISKT ITQSGHRLLI RTLTSPSTDL DLINKRLALV
QSFFDREDLR EEIRDILRNV EDIMRIIQRF RTRRGSSRDI WDVGIWIRTI EGIIARINEE
IAYEIQNYGN RAKSEGVLRL QELTRTFAPL GELATKIEES IDENAILWNP APDDIDDGSE
DPGEAMLGEE SDLLDKKEAK ETKKERIERE KQEREDRQWW ILPSFSQELQ SLHDDLAQLK
KERDKLQADL VKRFSTPQLK LVKSVRYGYH IQMTISEATK VEKARSLERI GGTSGKIAYF
AHGAWSALGA KTEIAMETLS MAQRRAERDL RNLVIEQADA IQVNAGLIDE LDLTMCFAQN
AKEMGWVRPS LDNTSDLNIV AGRHPSIESS LLQSSRSFTP NDTLMTRSNH LHIITGPNQG
GKSTLLRQTA VITILAQSGS FVPAQKAKIG IVDKVFSRIG ARDDLWRDRS TFMLEMVETA
AILKHATPKS LVIMDEIGRG TTLQAGVSIA YSTLNYILNN IGCKTMFATH YHELGRMLGY
EDEYGSPTKK GKIARKGVEY WCTDVDEVDG AFSYSYKLKP GINHKSHAIK AARLAGMPDS
FLHTAEHTLK YIQQTGRFDP PAEAISS
//
