ID A0A1B9IHU3_9TREE Unreviewed; 1586 AA.
AC A0A1B9IHU3;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=SEC7 domain-containing protein {ECO:0000259|PROSITE:PS50190};
GN ORFNames=L486_07647 {ECO:0000313|EMBL:OCF54991.1};
OS Kwoniella mangroviensis CBS 10435.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1331196 {ECO:0000313|EMBL:OCF54991.1, ECO:0000313|Proteomes:UP000092583};
RN [1] {ECO:0000313|EMBL:OCF54991.1, ECO:0000313|Proteomes:UP000092583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10435 {ECO:0000313|EMBL:OCF54991.1,
RC ECO:0000313|Proteomes:UP000092583};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Kwoniella mangroviensis CBS10435.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10435 {ECO:0000313|Proteomes:UP000092583};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI669468; OCF54991.1; -; Genomic_DNA.
DR STRING; 1331196.A0A1B9IHU3; -.
DR Proteomes; UP000092583; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF388; GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000092583}.
FT DOMAIN 1066..1254
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 83..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 217..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 348..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 501..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 623..746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 797..936
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1447..1491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..376
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..403
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..549
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..663
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..746
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 815..829
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 854..884
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1465..1491
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1586 AA; 173935 MW; 837B5608BA71FE1E CRC64;
MGSPTKQHFY ASRPSSRAGS RPTSPSTPAE VRSQAVAKLK RAASLPRRPD GRRPSLAQAI
NAEHSTVTNH QTAQTFNTQN ENTNTLSDQQ QQQQYAGPST LDVSPNPSEP QEVLSPSPVA
TTFDHSNMYP SPTPGPAMQM QRSVSANSTY HMASPIGLHT PPAADWAAMQ LAQSYLPSLT
PTCLSPNPYP HSVPIGVGRN IPSPLPTLGE LATLQRSNSN AARAHAMSKL TGGKQAPQPE
DEFTLSTPSR VNLTRAGTLG GPRMLGLAIN KSHAAEAPME DTSPVLTLAE ARPRLQRSFT
VSSSNMGEER RSAVGRRMVE RLAERRAARQ KEEEEVRKLW EERRAQAEVV GAEQHVDQDD
EDQDVPGEEA GDDDNNYYNE NQEQADPNQH YHQDRDGHHY EARPDNGIPQ FARHSPQEPP
QPEFIPAHGG DLLAAEAASG DRPISRGTMI STQEPFEYED HLRRSLSSRT ARGAVGTAEP
LPSIVTPEHD NQRYTENLAH TDVQVSDEPL LPPKPSYATP TRPGHAPHSS TSTESTIQGS
QSPGGSTLSG LDSMMFVMGG SSLPGSAGLR PPGNGQHWPQ EVHEGSEWGT PAKDLHQATF
TDSPILHSPA EFHQTQVPLT EVPVDDEGDL TPPSRTTTRT DSMMSWEEVG GKEDQEIRVP
TDKTYHQKTG SFSAKLKGSV RSAMKKRSQS RTSITSFTQS PPASPMNLQP ATFSRRGSES
SNSPSYSKEH SPRHQPSVSS LSPSIAPDPQ AALLLQHQLS NEPSQISFLP RANLNDPRIM
SAKLSPFPGI AQLERKNTDG TLAPGEPPKL IHQVSDSAVP SQQRATPPVV QESIYALPLP
ASHPDDRRAS ADSATKRNWL SKAFGHSTSP RSSGSVSRKS SSPDVAGEAR TLGQGAQIIS
SDVDPFAPPP PPQQTLGVKP ARHRSASPSV SVVPELSEEG SRFTRFISMR GENNTPAVPE
QMEENLDQRS KDVLTRMDAV LAMGPDDPAR PEILDDPPRK LLLSSQILQV VNTHTVKDRY
LFLFNDILVI AKPIISHGIH ATLDMKYLVK SIVSLDRLAI SGFNEEPTAE PPRHPVVTNF
IERFAQDPVS ACAYLVERSN PKVDTATLAS LIFKTPELDK AQVGYLLANN DKLMRHFIDR
FNFSNIRIDE ALRMFLLSVR LPTERTSCEN LLRGFGYRYF EANQSHISYD RELAAELVLA
IIQFNDSLYG TFGFSLPNHA INEETFVSAF QSKDPRGLVP VELLSEIFTS VKQTELVQSL
DSSKEVGRSK QIAINPRIPS KLSYNTWSEK ITISIPTSDP SFKIKLLGEG LVFEPPLLDF
ANSSEQSFRV KGTSLGVRHL LFNRTGSNAA LYGNLGNTRL FTIERAFMKY TFHVSFTSHL
GLKRKYCFSL NDLESKRRWG KLLSKQINLT KQTKSSAITT VQEKIRQTAE NVSIQVLRDA
LIPSEWKSQH QPIDTSAAIP NGGGGSMDNY NNRGRSSASK EKTTRSGSVS ISYTKPLKEE
YDLGPLVPTK STNPPLGLNG QERQSGIMEI QTGKELVLLC RQNSLLPGLL GLLHSAKEGA
EDVRSLKVGN EMIERNDSLR NKGLRV
//
