ID   A0A1B9IT40_9TREE        Unreviewed;      1038 AA.
AC   A0A1B9IT40;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Sulfatase-modifying factor enzyme domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=L486_03193 {ECO:0000313|EMBL:OCF58703.1};
OS   Kwoniella mangroviensis CBS 10435.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Kwoniella.
OX   NCBI_TaxID=1331196 {ECO:0000313|EMBL:OCF58703.1, ECO:0000313|Proteomes:UP000092583};
RN   [1] {ECO:0000313|EMBL:OCF58703.1, ECO:0000313|Proteomes:UP000092583}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 10435 {ECO:0000313|EMBL:OCF58703.1,
RC   ECO:0000313|Proteomes:UP000092583};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA   Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA   Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Kwoniella mangroviensis CBS10435.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000092583}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 10435 {ECO:0000313|Proteomes:UP000092583};
RA   Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA   Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT   "Evolution of pathogenesis and genome organization in the Tremellales.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KI669461; OCF58703.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1B9IT40; -.
DR   STRING; 1331196.A0A1B9IT40; -.
DR   Proteomes; UP000092583; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1580.10; paralog of FGE (formylglycine-generating enzyme); 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR019257; MeTrfase_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR005532; SUMF_dom.
DR   InterPro; IPR042095; SUMF_sf.
DR   PANTHER; PTHR43397; ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1; 1.
DR   PANTHER; PTHR43397:SF1; ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1; 1.
DR   Pfam; PF03781; FGE-sulfatase; 1.
DR   Pfam; PF10017; Methyltransf_33; 3.
DR   SUPFAM; SSF56436; C-type lectin-like; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000092583};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          58..106
FT                   /note="Histidine-specific methyltransferase SAM-dependent"
FT                   /evidence="ECO:0000259|Pfam:PF10017"
FT   DOMAIN          173..256
FT                   /note="Histidine-specific methyltransferase SAM-dependent"
FT                   /evidence="ECO:0000259|Pfam:PF10017"
FT   DOMAIN          373..559
FT                   /note="Histidine-specific methyltransferase SAM-dependent"
FT                   /evidence="ECO:0000259|Pfam:PF10017"
FT   DOMAIN          780..1035
FT                   /note="Sulfatase-modifying factor enzyme"
FT                   /evidence="ECO:0000259|Pfam:PF03781"
FT   REGION          1..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          111..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..42
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        113..134
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1038 AA;  117600 MW;  0BD243A21E541872 CRC64;
     MPSSNTRTTI FTLPVPAADA GSNTPQPTLR EQIESSLKGT TDIQYPGDRE EDRSWGYKRR
     IPTLVLYDEE GLRLYDKITS SAPEYYPFPD ELHLLKEYGQ EIAQSMGFPC TRRHRRSPRD
     EINNNDEVPD KPWKPAKWGD AALGRFNDGV NGEEGLAGED AWRKEQKEGE GWDVVELGAG
     ALRKTAHLLL ALSSSINPSS ESNTAAPIRY HPLDLSEPEL RRVLAEMEDG FGDQLRGKVE
     CIGLHGDYEA GLQFIREGKL SSLNVKSEED NENFPTPPFA LIDENDGIAI PLKKDEETKE
     PSPLLSPESI NIVTPRSEIS CLPSEITEST PSCNTNDNDA GTWSPISSAE YDDHTQYGTR
     QAQGNSDNVT EVKRSFLHST STVDTEPSGR PLHLVFLGSS LGNFDRESAA PFLRSLPLRK
     GDTLLLGLDG RPTQGKEGNR KVEVAYNDPS GHTKRFEEHG WDVVKKELSL GNDNQVEFVG
     RYNEVLGRHE AYFKSTNQQT IHLPSSDEDI VLEKDELLNI EWSYKYSLSE ALNLFSQANL
     RVVNSWKAPN SEYRLWVLER PEVIFDLNSS FSSKLALEVM DNAQDEDAVE RAQGVPKWND
     WLDLWKFWDH ITLQMIPKEM LHKKPIDLRH ICLFYLGHIP TFLDIHLTRL TKGSHTEPEY
     FKTIFERGID PDVDDPTKCH DHSEVPMSEE DWPVLSEILA FRDRVRLRLK GIYDSLSSGR
     RPFSRHTGRV LFMTYEHEAM HAETLLYMLA QSEMTRPPTA VSTPQWDILA EQWNSDLQEN
     KVITIEGGQV ELGHRDLEAD DMDHPTIDGW ETHEFGWDNE HTNIAKSIKG FKIDSLTISN
     SDYLSYLQST GKFSGLSKDT APASWMYDET KGEWNVRSLY GPLSFEVAGR WPLMASKLEF
     EDYAKYKKGR LPTEEELRML YETEQGPRTI GEGVNTGVKN WHPTPPINAT TDNAGKIIPG
     HNGGVWEWTD TPFKGLNGFV PSVIYPGYSK DFFDGKHYVV LGGSYVTIPS IAGRKSFRNW
     YQANYRFSFV GARVAYDL
//