ID A0A1B9IVZ1_9TREE Unreviewed; 1053 AA.
AC A0A1B9IVZ1;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
GN ORFNames=L486_02365 {ECO:0000313|EMBL:OCF59693.1};
OS Kwoniella mangroviensis CBS 10435.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1331196 {ECO:0000313|EMBL:OCF59693.1, ECO:0000313|Proteomes:UP000092583};
RN [1] {ECO:0000313|EMBL:OCF59693.1, ECO:0000313|Proteomes:UP000092583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10435 {ECO:0000313|EMBL:OCF59693.1,
RC ECO:0000313|Proteomes:UP000092583};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Kwoniella mangroviensis CBS10435.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10435 {ECO:0000313|Proteomes:UP000092583};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the post-replicative DNA mismatch repair system
CC (MMR). {ECO:0000256|RuleBase:RU003756}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|RuleBase:RU003756}.
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DR EMBL; KI669460; OCF59693.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B9IVZ1; -.
DR STRING; 1331196.A0A1B9IVZ1; -.
DR Proteomes; UP000092583; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 3.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003756};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003756};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003756};
KW Reference proteome {ECO:0000313|Proteomes:UP000092583}.
FT DOMAIN 916..932
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 597..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1053 AA; 117627 MW; E2BDBE257104CF61 CRC64;
MSLVRVRQCI RLGGNSKPIL KSLICGKSFS TTDTIRKAAS RSEKITTSFN LSDLPTRALG
DDGQPLPPLG KWREDVVSHA KMDNLQNALP HLDTAVLSPA EEQAEVDRAI AAGIIPSSDL
SREVYTNWLR FPDCILLTRV GKFYESYFEP ARQLSSILNI KLAQKSYKGK DIERKFPFAG
FPVAALDKYL KILVQELGHT VVIVEEYDEE GSIAYVGKKL TAATGPKERR VYRVVTPGTM
VDEGWLDGNE SRYLLAISLG RDNIDLDGKK STKMTLAYTD ASTGEFFTKD TTLANMEDEL
ARIAPREVVL DRSLLSLWQD NTIRPNPNIG IATTDLFNLL QVLGVHVSFA DPYQSPPLWS
SNILPSDIPS RPRNTEGIAI ALLRHHLQYA LRESMPTLTQ PSRQVSEAQV QIDAATLQAL
EIRHALRPGG LVAIGERQTI SPVSSRGTLL SVISKTVTQS GHRLLIRTLT SPSTSLEIIN
SRLALVQAFH DREDLRAELR DVLRGIEDVM RIVQRFRGQR GSNRDIWDVG VWIRTVEGIL
NRIKGELAYE IQNDTDRAGS EGVLRLQELI GEFQPLGDLA KKIEDSIDEN AIMWSSAPEE
SEDGDEDPGE AMIANEGDRA SSKETKESKK DRIDREKQEK EDRQWWILST FSKELQAVHE
ELATLKREKE KLQSELAKRY ATPNLKLLKG MRYGYHVQMT SSEASKVEKA RSLERIGGTS
GKIAYFAHGP WSALGAKTEI AMETLSIAQR RAERDLRNMI TEQADKIQKN AELVDEIDLT
MSFAQNAKEM GWVRPELDDS NDLDIIAGRH PSIESSLLQS SRTFTPNDTH MNSSSHLHII
TGPNQGGKST LLRQTAVIAI LAQSGSFVPA EKARIGIVDK VFSRIGARDD LWRDRSTFML
EMVETAAILK NATRKSLVIM DEIGRGTTLQ AGVSIAYSTL DYILKRIGCR TMFATHYHEL
GRMLAYGDDR NGREEMGRKG VEYWCTDVDE VDQAFSYSYK LKPGINHQSH AIKAARLAGM
PESFLQTAED TLKHVQKTGR FDPPSTVSQL KNT
//
