ID A0A1B9J1Y4_9TREE Unreviewed; 1258 AA.
AC A0A1B9J1Y4;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Cyclin-dependent protein kinase inhibitor {ECO:0000313|EMBL:OCF61664.1};
GN ORFNames=L486_01322 {ECO:0000313|EMBL:OCF61664.1};
OS Kwoniella mangroviensis CBS 10435.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1331196 {ECO:0000313|EMBL:OCF61664.1, ECO:0000313|Proteomes:UP000092583};
RN [1] {ECO:0000313|EMBL:OCF61664.1, ECO:0000313|Proteomes:UP000092583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10435 {ECO:0000313|EMBL:OCF61664.1,
RC ECO:0000313|Proteomes:UP000092583};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Kwoniella mangroviensis CBS10435.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10435 {ECO:0000313|Proteomes:UP000092583};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI669459; OCF61664.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B9J1Y4; -.
DR STRING; 1331196.A0A1B9J1Y4; -.
DR Proteomes; UP000092583; Unassembled WGS sequence.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd14483; SPX_PHO81_NUC-2_like; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR24203; ANKYRIN REPEAT FAMILY PROTEIN; 1.
DR PANTHER; PTHR24203:SF45; DIEGO, ISOFORM A; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF03009; GDPD; 1.
DR Pfam; PF03105; SPX; 2.
DR SMART; SM00248; ANK; 7.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 5.
DR PROSITE; PS51704; GP_PDE; 1.
DR PROSITE; PS51382; SPX; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000092583};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..241
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT REPEAT 435..467
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 468..490
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 502..534
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 534..558
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 572..607
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 880..1168
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
FT REGION 49..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 92..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 167..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 855..900
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1258 AA; 137720 MW; 45EEDD8F02C84B81 CRC64;
MKFGKTIQSQ QVPGWGEYYL NYKALKKIIN SYAAGRPASD ASLLSLGLRP AKKSPGSGSN
KSDPDAGSLS PPHLQQHDTS ITPSSIVEDL EPLPAESEPP APNTGSALMS RDPTGGNDRS
ESFKAHRDVF FFTLQRELEK INTFYLVKER DLRLRLLTLL SNRKRLLQNS SGSGTPGEDS
TLDNSTRKDA EWISLEEGWR LFERDLGKLQ GFIEINATGF RKILKKWDKR SKSNTKELYI
ERQVEVQPCF NREFIAKLSD IVTANLLDIE NGSEHLSTSF LEIEHNLPES IGADGLNLGS
GRKGDFGEID VLESTGNSLA LDALVDLDSN MLKAFSSGKD AILDWLRIAK AKQNQYQRQD
KSTSTRLMRI LWRAAQHVPQ EYLDMVLNAV TLDYNYIDNI NGRSPAHQAA INGSLTLIGL
CAQNNVGLLE KPDAYDRRPI HYASMHGHSE IVSFLLSQSV DPSATDKDGY TPLMHAITQG
HLEVVRIFVQ DKLTLEPTAI SNDLIPLSLA CQYGHLEVAR LLLQCGAKVI PNSEGLYPQH
FAAKAGHEQI CRLLVEEGGP DGGGKDRQDK YNLWTPLHHA AIGGQPQHLA CIKVLVEAGC
NVNAADEYGK SPGWYSAWFG HVECLNYLLD SGAKLNGNQN TLQGMENLGL AADPQMDSLS
PGSDLMLDPP ADEFELIPSL SLPPPIIPLR VYGHEFLANR CLIQLSLGHP FTRPSSSSKA
PPIKLYSRSG QDPLNLWSSL KLVMTSKSDI SAVPHSVILP LADEREVFSF QVQSLETFTL
ELSLYPTFGS KVIGRAIVLP ATFNDVTYHK GIVAPLLDHN LKTIGEVAFE VSCIKPFQGA
QLEIGGRVET YWKSKVTPSQ PTQDHAHQFQ SHRPLSVSTS SPSLRPPAIT SAPSSNTNHE
SALVTASSLS GEYVHVVVQV TKDGVPVIYP NIKLPVDNLD ITVSDVTLEQ FLLIGKSQNL
LLDPSSSSLS SVEWSSILSK TMSTLDSILN VLPSDIGLNL LLQYLRPKTI QLRNYGKSIE
INKWVDTILH SIYENGKAQS QSQQKGRKFI FSSFEPEVAT ALNWKQPNYA VFFASNCGIS
SSSSSTPSTT TTDRKRLIPI SQEEETDLRC LSVREAVNFA KSTNLLGVIL EATTLAAVPS
LVASVKDAGL LLATFGDTQD ITSLRQGASD GRTIDAFVID GTPSPIEVVY SLSDKFPVPG
RTEINMKAAN DETNRNNNNN STGGSTLQVQ DLLALGKRFE FEATESVSGG PVDFIAAN
//
