ID   A0A1B9NIR5_9MICO        Unreviewed;       688 AA.
AC   A0A1B9NIR5;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=prolyl oligopeptidase {ECO:0000256|ARBA:ARBA00011897};
DE            EC=3.4.21.26 {ECO:0000256|ARBA:ARBA00011897};
GN   ORFNames=A7J15_11000 {ECO:0000313|EMBL:OCG76509.1}, E3O41_05250
GN   {ECO:0000313|EMBL:QBR73885.1};
OS   Microbacterium sediminis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Microbacterium.
OX   NCBI_TaxID=904291 {ECO:0000313|EMBL:OCG76509.1, ECO:0000313|Proteomes:UP000093355};
RN   [1] {ECO:0000313|EMBL:OCG76509.1, ECO:0000313|Proteomes:UP000093355}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YLB-01 {ECO:0000313|EMBL:OCG76509.1,
RC   ECO:0000313|Proteomes:UP000093355};
RA   Lavstsen T., Jespersen J.S.;
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:QBR73885.1, ECO:0000313|Proteomes:UP000295661}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YLB-01 {ECO:0000313|EMBL:QBR73885.1,
RC   ECO:0000313|Proteomes:UP000295661};
RA   Yu L.;
RL   Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:QBR73885.1, ECO:0000313|Proteomes:UP000295661}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YLB-01 {ECO:0000313|EMBL:QBR73885.1,
RC   ECO:0000313|Proteomes:UP000295661};
RA   Xu X.;
RT   "Genomic analysis of Microbacterium sediminis YLB-01 reveals backgrounds
RT   related to its deep sea enviroment adaptation.";
RL   Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of Pro-|-Xaa >> Ala-|-Xaa in oligopeptides.;
CC         EC=3.4.21.26; Evidence={ECO:0000256|ARBA:ARBA00001070};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LXMD01000001; OCG76509.1; -; Genomic_DNA.
DR   EMBL; CP038256; QBR73885.1; -; Genomic_DNA.
DR   RefSeq; WP_067027920.1; NZ_KV744790.1.
DR   AlphaFoldDB; A0A1B9NIR5; -.
DR   STRING; 904291.A7J15_11000; -.
DR   KEGG; msed:E3O41_05250; -.
DR   OrthoDB; 9801421at2; -.
DR   Proteomes; UP000093355; Unassembled WGS sequence.
DR   Proteomes; UP000295661; Chromosome.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 2.130.10.120; Prolyl oligopeptidase, N-terminal domain; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR023302; Pept_S9A_N.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR002470; Peptidase_S9A.
DR   PANTHER; PTHR42881; PROLYL ENDOPEPTIDASE; 1.
DR   PANTHER; PTHR42881:SF2; PROLYL ENDOPEPTIDASE; 1.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   Pfam; PF02897; Peptidase_S9_N; 1.
DR   PRINTS; PR00862; PROLIGOPTASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF50993; Peptidase/esterase 'gauge' domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000093355}.
FT   DOMAIN          25..402
FT                   /note="Peptidase S9A N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02897"
FT   DOMAIN          479..684
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
SQ   SEQUENCE   688 AA;  74717 MW;  EB0257A2BE7D1737 CRC64;
     MRYPEVRRDD IIDEFPLPDG STARVPAPYR WLEDSDSDET RRFIEAQNAF AEPILAALPA
     RAAFRERLTA LLSRPTRGVP LQRGGRVFAW HGDGRNQDVL VVADDVDGLE DARVLLDPNE
     LSRDGTVAVT MMTVSPDGAY VAYGVADGGS DWRTIRVRDV ATGEDLDDVI EWTKWNHPIW
     HPDARSFSYW AYDAPSDDPL VDQMGTGRLL LHRLGTPVSE DELLFTRPEE PRTFGREWPR
     DDAWFVFSTD TGSSSGNDLA VRRHDEPMSA LRPLATGHER EWNAIGIRDD VLYVVTDADA
     PRYRLVAFDL AAADPAASLR EVVPQHAEDV LLDAGLTASG LVLTYSHDAS HRMQLATFDG
     ALGDALPIGA GVSVAESDAV SATDTVFVKA QGFVDPGTRH EVVVDGARVV AHRTLPDPAT
     GAIRATTTRI RATSADGTVV PAFVVAPEGA AHGPRPTLMW GYGGFNIPMN PGYRPLFAAW
     VQAGGTLVVP NLRGGGEFGS DWHKAGTKER KQNVFDDLFA VAERIIADGL TTPQQLALHG
     RSNGGLLAAA ALTQRPDLWA AVLPGVGVLD MLRFHRFTIG WAWTSDYGDP DDPEAFAYLR
     AYSPLHNLVE GRAYPPTLIT TGDHDDRVVP GHSFQFAAAL QHAQGGDAPI LLSVDTRAGH
     GMGKPRDAQA LEFADQLAFA ARFTGLEA
//