ID   A0A1B9XXD0_9FLAO        Unreviewed;       618 AA.
AC   A0A1B9XXD0;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=DNA topoisomerase (ATP-hydrolyzing) {ECO:0000256|ARBA:ARBA00012895};
DE            EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
GN   ORFNames=BA195_11330 {ECO:0000313|EMBL:OCK42210.1};
OS   Tenacibaculum soleae.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Tenacibaculum.
OX   NCBI_TaxID=447689 {ECO:0000313|EMBL:OCK42210.1, ECO:0000313|Proteomes:UP000093186};
RN   [1] {ECO:0000313|EMBL:OCK42210.1, ECO:0000313|Proteomes:UP000093186}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCD-KL19 {ECO:0000313|EMBL:OCK42210.1,
RC   ECO:0000313|Proteomes:UP000093186};
RA   Eisen J.A., Coil D.A., Lujan K.M.;
RT   "Draft Genome Sequence of Tenacibaculum soleae UCD-KL19.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP-dependent breakage, passage and rejoining of double-
CC         stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OCK42210.1}.
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DR   EMBL; MAKX01000024; OCK42210.1; -; Genomic_DNA.
DR   RefSeq; WP_068705635.1; NZ_MAKX01000024.1.
DR   AlphaFoldDB; A0A1B9XXD0; -.
DR   STRING; 447689.BA195_11330; -.
DR   OrthoDB; 9802808at2; -.
DR   Proteomes; UP000093186; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   CDD; cd00822; TopoII_Trans_DNA_gyrase; 1.
DR   CDD; cd01030; TOPRIM_TopoIIA_like; 1.
DR   Gene3D; 3.30.230.10; -; 1.
DR   Gene3D; 3.40.50.670; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR   InterPro; IPR001241; Topo_IIA.
DR   InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR   InterPro; IPR013759; Topo_IIA_B_C.
DR   InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR   InterPro; IPR018522; TopoIIA_CS.
DR   InterPro; IPR006171; TOPRIM_domain.
DR   PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR   PANTHER; PTHR45866:SF2; DNA TOPOISOMERASE (ATP-HYDROLYZING); 1.
DR   Pfam; PF00204; DNA_gyraseB; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF01751; Toprim; 1.
DR   PRINTS; PR00418; TPI2FAMILY.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00433; TOP2c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR   SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR   PROSITE; PS00177; TOPOISOMERASE_II; 1.
DR   PROSITE; PS50880; TOPRIM; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:OCK42210.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000093186}.
FT   DOMAIN          408..514
FT                   /note="Toprim"
FT                   /evidence="ECO:0000259|PROSITE:PS50880"
SQ   SEQUENCE   618 AA;  70508 MW;  0A625A459C1D3F9C CRC64;
     MAQETKYTED NIRSLDWKEH IRMRPGMYIG KLGDGTSPDD GIYILVKEVL DNSIDEFVMG
     TGKTIEVSVQ GEKVIVRDYG RGIPLGKVVD VVSKMNTGGK YDSRAFKKSV GLNGVGTKAV
     NALSTFFRVE STRDGKSASA EFEKGELVNQ DLLEETSRRR GTKVTFIADN SIFKNYKYRP
     EYIIRLLKNY VYLNPGLTIV FNGEKFHSKN GLKDLLEDNN NQDDMLYPII HLRGDDIEVA
     ITHSKTQYSE EYHSFVNGQH TTQGGTHQAA FREAIVKTIR EFYGKNFDAS DVRKSIISAI
     AIKVMEPVFE SQTKTKLGST EMGGDLPTVR TYINDFIKTK LDNFLHKNVE IADKLQKKII
     QAEKERKELS GIRKLAKDRA KKASLHNKKL RDCRIHLGDI KKENHLDTTL FITEGDSASG
     SITKSRNVNT QAVFSLKGKP LNSYGLSKKI VYENEEFNLL QAALNIEDGL EDLRYNNIVI
     ATDADVDGMH IRLLLITFFL QFFPEVIKER HLYILETPLF RVRNKKETIY CYSEDEKRAA
     IDKLRGKPEI TRFKGLGEIS PNEFVHFIGD DIRLDPVMLD KEMSIEQMLE FYMGKNTPDR
     QKFIIENLKV ELDAIEEV
//