ID   A0A1C0AK46_9ACTN        Unreviewed;       473 AA.
AC   A0A1C0AK46;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Sodium:alanine symporter {ECO:0000313|EMBL:OCL32984.1};
GN   ORFNames=BCR15_06775 {ECO:0000313|EMBL:OCL32984.1};
OS   Tessaracoccus lapidicaptus.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Propionibacteriaceae; Tessaracoccus.
OX   NCBI_TaxID=1427523 {ECO:0000313|EMBL:OCL32984.1, ECO:0000313|Proteomes:UP000093501};
RN   [1] {ECO:0000313|Proteomes:UP000093501}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IPBSL-7 {ECO:0000313|Proteomes:UP000093501};
RA   Florea S., Webb J.S., Jaromczyk J., Schardl C.L.;
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OCL32984.1}.
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DR   EMBL; MBQD01000023; OCL32984.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C0AK46; -.
DR   Proteomes; UP000093501; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000093501};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        153..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        195..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        222..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        249..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        316..336
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        358..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        400..421
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        427..444
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   473 AA;  49683 MW;  7225DCAA550C875F CRC64;
     MKGVDVEALT TLLEEIAGFV WGPFLLIPLL LLTGLWLTIK LRGIQFRTLG SALRLALWER
     KDADAEGGDI SQFQALTTAL AATVGVGNIV GVATAISMGG PGALFWMWVT GLVGMASKYS
     EAFLAVRFRT VDAKGDASGG PQYYLKKALP GGWGVALSII FAVFAVLASF GIGNMTQANS
     VAANAQNAFG IDPQISAIVM AVFTGLVILG GIRAIGTVTA ALVPFMIVFY ILGALYILIV
     NIVDVPGALV LIFGQAFTGP GMAGGAFGSF MLAVQYGVAR GIFSNESGMG SAAIAAAAAQ
     TTHPVRQGLV SMTQTFIDTI VVVSFTGLVL VTTGVWDDGE SPALLTSMAF SHGLPGNWGG
     YIVAIGVILF AFSTILGWSY YGDRCVERLF GARATLAYRI LFTIVVYIGA TVPLGVVWAF
     ADIMNGLMAL PNLVGLLLLS GLIARETSHY LKNDPKLRAN RAQVDAFMAD QVR
//