ID A0A1C0APV5_9ACTN Unreviewed; 798 AA.
AC A0A1C0APV5;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Macrolide export ATP-binding/permease protein MacB {ECO:0000313|EMBL:VEP39603.1};
GN Name=macB_1 {ECO:0000313|EMBL:VEP39603.1};
GN ORFNames=BCR15_00295 {ECO:0000313|EMBL:OCL36356.1}, TLA_TLA_00978
GN {ECO:0000313|EMBL:VEP39603.1};
OS Tessaracoccus lapidicaptus.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Tessaracoccus.
OX NCBI_TaxID=1427523 {ECO:0000313|EMBL:OCL36356.1, ECO:0000313|Proteomes:UP000093501};
RN [1] {ECO:0000313|Proteomes:UP000093501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IPBSL-7 {ECO:0000313|Proteomes:UP000093501};
RA Florea S., Webb J.S., Jaromczyk J., Schardl C.L.;
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OCL36356.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IPBSL-7 {ECO:0000313|EMBL:OCL36356.1};
RA Puente-Sanchez F., Arce-Rodriguez A.;
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:VEP39603.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TLA_E {ECO:0000313|EMBL:VEP39603.1};
RA Peiro R., Begona, Cbmso G., Lopez M., Gonzalez S., Sacristan E.,
RA Castillo E.;
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Proteomes:UP000516347}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Peiro R., Begona, Cbmso G., Lopez M., Gonzalez S., Sacristan E.,
RA Castillo E.;
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family.
CC {ECO:0000256|ARBA:ARBA00038076}.
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DR EMBL; MBQD01000011; OCL36356.1; -; Genomic_DNA.
DR EMBL; LR214441; VEP39603.1; -; Genomic_DNA.
DR RefSeq; WP_068750523.1; NZ_MBQD01000011.1.
DR AlphaFoldDB; A0A1C0APV5; -.
DR Proteomes; UP000093501; Unassembled WGS sequence.
DR Proteomes; UP000516347; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR003838; ABC3_permease_dom.
DR InterPro; IPR025857; MacB_PCD.
DR PANTHER; PTHR30572; MEMBRANE COMPONENT OF TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR30572:SF18; MEMBRANE PROTEIN-RELATED; 1.
DR Pfam; PF02687; FtsX; 2.
DR Pfam; PF12704; MacB_PCD; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:VEP39603.1};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000313|EMBL:VEP39603.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000093501};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 659..691
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 712..741
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 761..781
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..206
FT /note="MacB-like periplasmic core"
FT /evidence="ECO:0000259|Pfam:PF12704"
FT DOMAIN 244..357
FT /note="ABC3 transporter permease protein"
FT /evidence="ECO:0000259|Pfam:PF02687"
FT DOMAIN 669..790
FT /note="ABC3 transporter permease protein"
FT /evidence="ECO:0000259|Pfam:PF02687"
SQ SEQUENCE 798 AA; 81405 MW; 2DF36316E9DA99E7 CRC64;
MFRHAVSELR LHPGRFIATL VAIAISVGFI VAISVFISTE QNGTGKANSM ALSTADLVAV
AGDEGLSAEA AELIGTVDGV AAVQRVINAS AEVTAGDRTV FATLWVNQAP EFRWAELAEG
AYPEAPGEIT VARDMADKLG VGLGDEVQAG PGQPLTVVGI TRDARSLFTS TGYLWQPADE
FPAAGAVAIL LAEDADPSAV ADEVVRAADG VAPGLTVQTA QEYRDAALVA TTGDFDVFKN
LLLAFAVIAV LVGMITIANT FTILLAQRRR QLGLLRAVGA SGSQVMGRMV LESLLLGLAG
SLVGVGLGFA VAAAGSAVTG SWYWGLTVDW AEVGLAVLVG VLATLISAVV PSVAAARVRP
LEALQAVPTE AQARRAGAVR AVVCGLLIAG GVALAVLSQV GRSEMNLVYA AASGVLLTLG
VLGAAPFFVP ALLRLAGRLA GPAGPTARLA LKNSARNPRR AAATASALML AIGLIVTLQI
ALTSARTSAM DTIDRELPLD LSATYESGVP AGTADAVRAV PGVAEVAVLP GKVVEVDGAS
YFAVDDHAAR LDMGVEAEPI PDTVARFDEV GPDTPATFAI GDVELTSETG ELYGWRAFGV
SAATLDRLPG QMVDAALWVK LTDRTDATAI NRAIAALAAE EQPDLSNSGA QMAGILEQVV
GVVILIMTAL LGVAVLIAVV GVGNTLGLSV LERQRESALL RALGMQRGQL QLMLLIEALA
LVLVGALVGF AAGIFFAWLG LSAAFAAVPG GTVDLRLAMD PAWTFGLVGV CLAAAALASV
LPGRRAAGAT PTEALAVD
//
