ID A0A1C0ARZ3_9ACTN Unreviewed; 504 AA.
AC A0A1C0ARZ3;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Acetyl-CoA hydrolase {ECO:0000313|EMBL:OCL37039.1};
DE SubName: Full=Succinyl-CoA:acetate CoA-transferase {ECO:0000313|EMBL:VEP40863.1};
GN ORFNames=BCR15_12330 {ECO:0000313|EMBL:OCL37039.1}, TLA_TLA_02089
GN {ECO:0000313|EMBL:VEP40863.1};
OS Tessaracoccus lapidicaptus.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Tessaracoccus.
OX NCBI_TaxID=1427523 {ECO:0000313|EMBL:OCL37039.1, ECO:0000313|Proteomes:UP000093501};
RN [1] {ECO:0000313|EMBL:OCL37039.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IPBSL-7 {ECO:0000313|EMBL:OCL37039.1};
RA Puente-Sanchez F., Arce-Rodriguez A.;
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000093501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IPBSL-7 {ECO:0000313|Proteomes:UP000093501};
RA Florea S., Webb J.S., Jaromczyk J., Schardl C.L.;
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000516347}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Peiro R., Begona, Cbmso G., Lopez M., Gonzalez S., Sacristan E.,
RA Castillo E.;
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:VEP40863.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TLA_E {ECO:0000313|EMBL:VEP40863.1};
RA Peiro R., Begona, Cbmso G., Lopez M., Gonzalez S., Sacristan E.,
RA Castillo E.;
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; MBQD01000003; OCL37039.1; -; Genomic_DNA.
DR EMBL; LR214441; VEP40863.1; -; Genomic_DNA.
DR RefSeq; WP_068749758.1; NZ_MBQD01000003.1.
DR AlphaFoldDB; A0A1C0ARZ3; -.
DR Proteomes; UP000093501; Unassembled WGS sequence.
DR Proteomes; UP000516347; Chromosome.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:OCL37039.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000093501}.
FT DOMAIN 7..222
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 329..469
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 294
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 364
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 384
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 388
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 408
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 504 AA; 54299 MW; FB74C6C7A17A89B7 CRC64;
MSGRIRNEAF KQKVMSAHDA AALVENGWNV GFSGFTGSGY PKVFPEALAA IIDAHHAKGE
EFRIGVWTGA STAPELDGAL ARTGGISYRA PYQSDPEMRS AINTGVSYYQ DIHLSHMGPQ
VSQGFLGHLN LAVVEATAIT EDGDIVPSSS VGMNRTYLDH ADKIIIEVNS WQSEDLFGMH
DIYYPIGALP PNRVPLPIQN AGDRIGGKVL KVDADKVVAV IETNSADRNT PFKALDDDSR
AIAGYFLDFL GNEVKAGRLP ENLLPLQSGV GNIANAVLAG LLEGPFENLT SYTEVIQDGM
VDLLDSGKLT VASATAFSLS PTAAEKMNDN AAHYRNKIVL RPQDVSNHPE AIRRMGVIAC
NGMIEADIYG NVNSTHVMGS RMQNGIGGSG DFTRNGWVSC FVTPSTAKGG AISCIVPMVN
HVDHTEHDVQ VLITEQGLAD LRGLAPRQRA IKVIENCAHP DYREPLLEYV KLAEKKANGH
HTPHDLATAL GWHVRFLETG TMAL
//
