ID A0A1C0BXY0_9FIRM Unreviewed; 466 AA.
AC A0A1C0BXY0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=PTS beta-glucoside transporter subunit EIIBCA {ECO:0008006|Google:ProtNLM};
GN ORFNames=A4S06_00305 {ECO:0000313|EMBL:OCN06190.1};
OS Erysipelotrichaceae bacterium MTC7.
OC Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC Erysipelotrichaceae.
OX NCBI_TaxID=1768196 {ECO:0000313|EMBL:OCN06190.1, ECO:0000313|Proteomes:UP000093409};
RN [1] {ECO:0000313|EMBL:OCN06190.1, ECO:0000313|Proteomes:UP000093409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MTC7 {ECO:0000313|EMBL:OCN06190.1,
RC ECO:0000313|Proteomes:UP000093409};
RA Whitehead T.R., Haley B.J.;
RT "Genome Sequence of MTC7.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCN06190.1}.
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DR EMBL; LVZN01000001; OCN06190.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C0BXY0; -.
DR STRING; 1768196.A4S06_00305; -.
DR OrthoDB; 92465at2; -.
DR Proteomes; UP000093409; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00212; PTS_IIB_glc; 1.
DR Gene3D; 3.30.1360.60; Glucose permease domain IIB; 1.
DR InterPro; IPR036878; Glu_permease_IIB.
DR InterPro; IPR018113; PTrfase_EIIB_Cys.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013013; PTS_EIIC_1.
DR InterPro; IPR001996; PTS_IIB_1.
DR PANTHER; PTHR30175; PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR30175:SF1; PTS SYSTEM ARBUTIN-, CELLOBIOSE-, AND SALICIN-SPECIFIC EIIBC COMPONENT-RELATED; 1.
DR Pfam; PF00367; PTS_EIIB; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR SUPFAM; SSF55604; Glucose permease domain IIB; 1.
DR PROSITE; PS51098; PTS_EIIB_TYPE_1; 1.
DR PROSITE; PS01035; PTS_EIIB_TYPE_1_CYS; 1.
DR PROSITE; PS51103; PTS_EIIC_TYPE_1; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000093409};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 119..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 436..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..90
FT /note="PTS EIIB type-1"
FT /evidence="ECO:0000259|PROSITE:PS51098"
FT DOMAIN 121..466
FT /note="PTS EIIC type-1"
FT /evidence="ECO:0000259|PROSITE:PS51103"
FT ACT_SITE 30
FT /note="Phosphocysteine intermediate; for EIIB activity"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00421"
SQ SEQUENCE 466 AA; 50142 MW; AA25B5D7D911234A CRC64;
MAKKKKYSEL ASKILELVGG PENIIFCEHC ITRLRFNVKD KSLINDKELD ELEGTNGRLW
VGDQLQVIIG TSVGGVYDEV CKQGKLETSD EIKENLDIPK ENKTVKDRLK GIVTTLTECI
VPALGAMVAM GMFAAIVSVI GPTGLNVVSV ESGVYKLLVM AQDGIMYFIP VVIAYTAARK
FNCSPIFAIL LVCIQLSSEW TTAVGDGSLT MFGIEPLAHT LNGQIIPVIL QIWIMSYVEK
GINKIMPDNF KFILVGVFEL LIMLPIALFI LTPGGMQLGL LLAYPITLLE SISPVLVSLV
AGGLYTLFVS VGMHSALSGI FVMDLFTTGV TYALLPSVFS QCWIFAALNI AIRVKTKNKA
LKETATESTI AAVVGGVMEP SIYAIYMKNI KIMIIACLGM AVTGATHRIL GVGVYALSAS
NFLGITAFLA GGMDNLLRAI PGILIGCIVV FAAIMILGVD KKEATK
//
