ID A0A1C0UZM1_9CYAN Unreviewed; 564 AA.
AC A0A1C0UZM1;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Precorrin-3B C(17)-methyltransferase {ECO:0000313|EMBL:OCQ90980.1};
GN ORFNames=BCR12_04235 {ECO:0000313|EMBL:OCQ90980.1};
OS Limnothrix sp. P13C2.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Pseudanabaenales;
OC Pseudanabaenaceae; Limnothrix.
OX NCBI_TaxID=1880902 {ECO:0000313|EMBL:OCQ90980.1, ECO:0000313|Proteomes:UP000093334};
RN [1] {ECO:0000313|EMBL:OCQ90980.1, ECO:0000313|Proteomes:UP000093334}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P13C2 {ECO:0000313|EMBL:OCQ90980.1};
RA Tan B., Te S.H., Gin K., Thompson J.;
RT "Draft genome of Limnothrix sp. P13C2.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCQ90980.1}.
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DR EMBL; MBRF01000026; OCQ90980.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C0UZM1; -.
DR STRING; 1880902.BCR12_04235; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000093334; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11646; Precorrin_3B_C17_MT; 1.
DR Gene3D; 3.40.50.11220; -; 1.
DR Gene3D; 3.30.420.180; CobE/GbiG C-terminal domain; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR021745; CbiG_mid.
DR InterPro; IPR021744; CbiG_N.
DR InterPro; IPR006363; Cbl_synth_CobJ/CibH_dom.
DR InterPro; IPR002750; CobE/GbiG_C.
DR InterPro; IPR036518; CobE/GbiG_C_sf.
DR InterPro; IPR038029; GbiG_N_sf.
DR NCBIfam; TIGR01466; cobJ_cbiH; 1.
DR PANTHER; PTHR47036; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR47036:SF1; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF01890; CbiG_C; 1.
DR Pfam; PF11761; CbiG_mid; 1.
DR Pfam; PF11760; CbiG_N; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF159672; CbiG N-terminal domain-like; 1.
DR SUPFAM; SSF159664; CobE/GbiG C-terminal domain-like; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:OCQ90980.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000093334};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OCQ90980.1}.
FT DOMAIN 1..69
FT /note="Cobalamin synthesis G N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11760"
FT DOMAIN 75..168
FT /note="Cobalamin biosynthesis central region"
FT /evidence="ECO:0000259|Pfam:PF11761"
FT DOMAIN 171..295
FT /note="CobE/GbiG C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01890"
FT DOMAIN 307..518
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 564 AA; 59958 MW; 826C907ED9CB1170 CRC64;
MIFVLAVGAT VRAIAPHLQD KRTDPAVVVV DETGHHVISL CGGHLGGADA LTRQVAGLLA
VEPVITSAAE GQQLPAIDLL GDRYGWRRGQ GDWLGVASAI ARFETVGVVQ TCGWNLWIEE
LPEFHPFVLL SEADLVDLDE LPPNLRAIVW ISDRPLPPLP LPAVAWHPRT LWVGIGCERH
TPEGQMAAAL SQVLEQADLA PEAIAGIGSI DLKQDEVGLL ALVDRLDLAA RWFTAAALAP
IAVPNPSEVV RSEVGTPSVA EAAARLAADG AELIREKQVF RAPNGGSGAC TIALARADRE
YTPHLGKLWL IGTGPGSLDQ LTPAARAALS QCDVIIGYQL YLDLLRPLLH PGQIIEGSPI
TREKQRAERA IDLAERGLRV AVVSSGDCGI YAMAGLVLEC LAARHWDGQT PQVEVLPGIT
ALQAAAARVG APLMHDFCAI SLSDLLTPWP VIVQRLQAAA AGDFVVALYN PRSQTRQTQI
ETAFEILRAK RSPETPVVLA RSLHRPDEQI TIATLATVDL QAIDMLTVVL IGNASTFTHS
GKVITPRGYA VANGILAATA PATD
//
