ID A0A1C0V469_9CYAN Unreviewed; 1811 AA.
AC A0A1C0V469;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BCR12_17525 {ECO:0000313|EMBL:OCQ92555.1};
OS Limnothrix sp. P13C2.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Pseudanabaenales;
OC Pseudanabaenaceae; Limnothrix.
OX NCBI_TaxID=1880902 {ECO:0000313|EMBL:OCQ92555.1, ECO:0000313|Proteomes:UP000093334};
RN [1] {ECO:0000313|EMBL:OCQ92555.1, ECO:0000313|Proteomes:UP000093334}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P13C2 {ECO:0000313|EMBL:OCQ92555.1};
RA Tan B., Te S.H., Gin K., Thompson J.;
RT "Draft genome of Limnothrix sp. P13C2.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCQ92555.1}.
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DR EMBL; MBRF01000019; OCQ92555.1; -; Genomic_DNA.
DR STRING; 1880902.BCR12_17525; -.
DR Proteomes; UP000093334; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:OCQ92555.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000093334};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:OCQ92555.1};
KW Transferase {ECO:0000313|EMBL:OCQ92555.1}.
FT DOMAIN 18..278
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1584..1809
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 1811 AA; 202315 MW; B50290416BA3FF40 CRC64;
MTSAPGSTNP AIAHLPAYQI LELMYEGTRT LVYRAVEKAT QRSVIIKVLS QEYPSFAELV
QFRNQYTVTK NLPIDGIVHP LSLIPYGNGY GLVMEDFGAI SLAQYLQDNT VTLVEILGIA
VRLVEILHEL HQYRVIHKDI KPTNILIDPT SKQVKLIDFG IASLLPKETQ SLQSPKSLEG
TLAYLAPEQT GRMNRAIDYR ADFYALGVTL YQMLTGELPF KGQDPLELIH CHMTQIPPAV
DVLNPQVPGM VAAIVNKLMA KNAEDRYQSA LGLKHDLEHC LNQYALQGRV AVFSLGDRDL
NDRFLIPEKL YGRHTEVQAL LDAFDRVAQG ASELMLVAGF SGIGKTAVVS EVHKPIVRQR
GYFIKGKFDQ FNRNIPFSAF VQAFRDLMGQ LLSESDQQLA QWRTKILTAL GTNGQVLIDV
IPELERIIGS QPPAPELSGA AAQNRFNLLF QNFLQIFTQA THPLVLFLDD LQWADSASLQ
LIKILMDGHP YLLLLGTYRD NEVSSAHPLM LTIEELKKAE VTLQTITLAP LGFRDTNQLV
AETLHCGLDR SRLLTELIYL RTQGNPFFTA QFLKALKEDG YILFDREQGV WECDLAPIST
LSLTDNVVEF MALQLQKLPT VTQGVLKLAA CIGNQFDLST LAIVSEQSET ETAAALWKAL
QEGLILPQSE VYKFYLGQET PEATETETTV SDRAVYRFLH DRVQQAAYAL IDDDQKQATH
LCVGRLLLEQ LSERDREERI FEIVNHLNVG QALIAAPNQQ RELAQLNFLA GCKAKAATAY
AAALTYIRTA IELLPEAIAQ KDYDLSFRLD KERAEVEYLN GNLEAAEIWI QRALGKAKTS
LEKADVYNMS ILQYTLQAKY PEAIQAGRQG LALLDIDLPV DHLEAALAQE LGQAKTLANH
NSFEVLTQLP IMTEPEQKMA IKLLISMGPP TYRSHQRLWS VICAKAVNLC LQYGNTPEIG
YIYPAFGGLR GYALNNYQGT DQLLDITLQL IQAFNNKSAE SVAYLMIGSS LRHWSDPLKI
ATEDYLSSYR VGLESSNLQY AAYAFGHNMY CRFYQSLPLD QLFDEITEYL NFSRKHKNQW
AIDLMLGGLS VVANLLDPEY DPTDLSIGWG KIQSELAYLE QCRIHKNWQV ICIFNILRTQ
VLLIFDQLEE AYYYGQQAES EIINVAPQGL LPYVHHCFVY ALLLAARYEQ TPEEQKARDW
TTIIRYRDQL KIWADNCPEN FLHLYFLVKA ETDRLTNQYP EAIESYDWAI ANAKGMGYLQ
EEALANELAA KFYMSWGKEK IAAVYLQEAY YCYARWGAKA KIRDLEIRYP KLLRPILQAS
STSVDFLNTL MTLTSVNPTI HSSTRKSASS ARLNQTLDFA SILRASQALS STIQLEELLG
QLTQIILQNS GAERCVLVLA DDRGSWQVRA TATLKSTQLG NDPLTDHSQV PAKLIRYVKN
TQELIVIDDL VTDLPVIGSY LNQHQPKSVL CLPILNQGQL LGCLYLENRL TAGVFTNDRV
IILNFLCTQA AISLNNAKLY QQVQQSFTDL QQAQLKLVQS EKMSALGSLV AGVAHEINNP
IGCIIGNIDA TQIYIEDLLG LLDLYAQELP NPSAQIQAEL EAVDLDYVRD DAMQLIRAMK
ESGDRIRAIS KSLRTFSRAD TESKQLFDVR EGIDSTVLIL RHRLKGNDHR PAIHVATNYD
PVPEIYCFPG QLNQVFMNLL ANAIDALDEA SQGHSFAALT AAAQAISIRV TSDQATVQVT
IADNGVGIPE EIIGKIFDQA FTTKAVGRGT GLGLAIARQI VVDIHGGSLE AKSTVGQGTE
FVIGLPIERP N
//
