ID A0A1C0VYB0_9CYAN Unreviewed; 531 AA.
AC A0A1C0VYB0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=BCD67_00045 {ECO:0000313|EMBL:OCR02737.1};
OS Oscillatoriales cyanobacterium USR001.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales.
OX NCBI_TaxID=1880991 {ECO:0000313|EMBL:OCR02737.1, ECO:0000313|Proteomes:UP000093314};
RN [1] {ECO:0000313|EMBL:OCR02737.1, ECO:0000313|Proteomes:UP000093314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USR001 {ECO:0000313|EMBL:OCR02737.1};
RA Te S.H., Tan B., Thompson J., Gin K.;
RT "Draft genomes of Oscillatoriales USR001.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCR02737.1}.
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DR EMBL; MBRE01000008; OCR02737.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C0VYB0; -.
DR SMR; A0A1C0VYB0; -.
DR REBASE; 171440; M.Ocy1ORF45P.
DR Proteomes; UP000093314; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR Gene3D; 1.20.1260.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR022749; D12N6_MeTrfase_N.
DR InterPro; IPR003356; DNA_methylase_A-5.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR038333; T1MK-like_N_sf.
DR PANTHER; PTHR42998:SF1; TYPE I RESTRICTION ENZYME HINDI METHYLASE SUBUNIT; 1.
DR PANTHER; PTHR42998; TYPE I RESTRICTION ENZYME HINDVIIP M PROTEIN-RELATED; 1.
DR Pfam; PF12161; HsdM_N; 1.
DR Pfam; PF02384; N6_Mtase; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000093314}.
FT DOMAIN 8..125
FT /note="N6 adenine-specific DNA methyltransferase N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF12161"
FT DOMAIN 147..479
FT /note="DNA methylase adenine-specific"
FT /evidence="ECO:0000259|Pfam:PF02384"
SQ SEQUENCE 531 AA; 59594 MW; 48199470E2D6206B CRC64;
MPANYTELEK RLWEAADELR ANSKLKPSEY SVPVLGLVFL LYADYKFGLV SQEIAVGSSS
RRRTVGKADY QAKGALYLPE TARFDYLIDR PEAEDIGGAI NAAMKAIADE NEELGGALPR
NYNSLEKPIL RELLKILNRI PRKNITEDAF GEIYQYFLGN FAQKEGQKGG EFFTPISLVK
LIVEVIEPNY GRILDPACGA GGMLVQSAIR VRNKLGFDPN QVISVYGQEK VDGTVKLCQM
NLAVHGVSGL RNIREGNTYY QDIHNSVGEF DFVMANPPFN VNGVDREKIK GDPHYPFGAP
TTDNANYLWI QLFYTALNRN GRAGFVMANS ASDARGSELE IRRQLIETGA VDVMIAIGSN
FFYTVTLPCT LWFFDRGKVK TARKDKVLFI DARHIYRQID RAHREFSEAQ IEFISNIVRL
YRGEKAELTA DSEMLIETFP DKVYRDVAGL CKIATLDEIE AQGWSLNPGR YVGVAQRQEA
EDFDFAARLE ELNEELEILN VEARGLEETI AENVVMLLED IVTIPGTCSQ N
//
