ID A0A1C0ZT02_9BACL Unreviewed; 1048 AA.
AC A0A1C0ZT02;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Beta-galactosidase {ECO:0000256|ARBA:ARBA00013303, ECO:0000256|RuleBase:RU361154};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756, ECO:0000256|RuleBase:RU361154};
DE AltName: Full=Lactase {ECO:0000256|ARBA:ARBA00032230, ECO:0000256|RuleBase:RU361154};
GN ORFNames=A8709_05920 {ECO:0000313|EMBL:OCT11215.1};
OS Paenibacillus pectinilyticus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=512399 {ECO:0000313|EMBL:OCT11215.1, ECO:0000313|Proteomes:UP000093309};
RN [1] {ECO:0000313|Proteomes:UP000093309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC13222 {ECO:0000313|Proteomes:UP000093309};
RA Zhang J., Zhang X.;
RT "Paenibacillus oryzae. sp. nov., isolated from the rice root.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412,
CC ECO:0000256|RuleBase:RU361154};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401, ECO:0000256|RuleBase:RU361154}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCT11215.1}.
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DR EMBL; LYPC01000028; OCT11215.1; -; Genomic_DNA.
DR RefSeq; WP_065858041.1; NZ_LYPC01000028.1.
DR AlphaFoldDB; A0A1C0ZT02; -.
DR STRING; 512399.A8709_05920; -.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000093309; Unassembled WGS sequence.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR004199; B-gal_small/dom_5.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR032312; LacZ_4.
DR PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR46323:SF2; BETA-GALACTOSIDASE; 1.
DR Pfam; PF02929; Bgal_small_N; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF16353; LacZ_4; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SMART; SM01038; Bgal_small_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361154};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361154};
KW Reference proteome {ECO:0000313|Proteomes:UP000093309}.
FT DOMAIN 744..1015
FT /note="Beta galactosidase small chain/"
FT /evidence="ECO:0000259|SMART:SM01038"
FT REGION 1022..1048
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1029..1048
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1048 AA; 118555 MW; 31557C22022055BB CRC64;
MSNNNVARDW DNLAVLERNR TKSRAYFIPH WDIAGALSYD RGSSPWFKSL NGNWKFHYAK
GPEWAQDDFY TADYDLSGWD EIQVPSHWQL KGYGHPHYTD LYYPFPVDPP HVPNDNPTGS
YVREFELPKL WDGRKLCVKF DGVDSAFHVW VNGNFVGYSQ GSRLTSEFDL TPYVKEGINR
MAVRVYQWSD GSYLEDQDMW YMSGIFRDVY LISEPSSLRM VDYRIVTELD AAYRDATLHV
EIELQGDAGG GEVQLQLLDY KGHSVISAKR QITLAGTDEA IVAFTIPVSK PSLWSAEAPT
LYHLTIGIVD QNVTVVETVA QRVGFRKIEV KDGQFLVNGK AILLKGVNRH DHHPDSGRTV
TVSTMIQDVK MMKQHNINAV RTAHYPNDPR FYDICDEYGL YVMEETDLET HGFEPLGNIS
RLSDDPAWQE AYVDRVRRMV DRDKNHPSVL FWSLGNESGF GCNFRAMSAW CKGADPTRLI
HYEEDREAEV CDIVSTMYSS VEKMVGFGQL VDHPKPHILC EFAHAMGNGP GGLKPYFDTF
DAYRRLQGGF VWEWIDHGIR RKTADGKDDY AYGGDYGDVP NNSNFVIDGL VQPDRTPSPG
LIEYKKIIEP VRVSYIEEGR IRIMNRYDFV TLEHLQAHWS VTVDGRTVQS GVLELPQIRP
GESAEVHVPL GEDMQLAVLA QEAERWLNVG FTLAVDCLWG EQGHEVAWAQ MTMEARANNS
SFAAIAARPP IQSLACTEEG RQLVLANDAF RIAFDTRQAG ISSLRMNGHE LVNTGPRLNF
WRAPIDNDMY VLPDWYKAHL NRLSERIDSC RWEQLSEGTV RITYTSRIAP PVFDWGFRCE
TTYTITGSGL IVMDVHGVPE GKTPAMLPKI GLQMEIPGDM DAVRWYGRGP GENYSDSKEA
GRFGVYSQSV DELLTPYIYP QENGNRTDVR WVSVTDGAGI GLLAVGAPTL EFSARRYTDA
DIEAAKHASD LVPRDFVTLN LDYRQNGLGS NSCGPAQSPE NTVTSEAFRF RIMLKPYLSE
DASPERLSHQ MRSEVQMNHH QQEGTNHA
//
