ID A0A1C1CNR6_9EURO Unreviewed; 1386 AA.
AC A0A1C1CNR6;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Double-strand break repair protein MRE11 {ECO:0000313|EMBL:OCT50121.1};
GN ORFNames=CLCR_06556 {ECO:0000313|EMBL:OCT50121.1};
OS Cladophialophora carrionii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=86049 {ECO:0000313|EMBL:OCT50121.1, ECO:0000313|Proteomes:UP000094526};
RN [1] {ECO:0000313|Proteomes:UP000094526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSF {ECO:0000313|Proteomes:UP000094526};
RA Teixeira M.M., Souza R.C., Almeida L.G., Vicente V.A., de Hoog S.,
RA Bocca A.L., de Almeida S.R., Vasconcelos A.T., Felipe M.S.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCT50121.1}.
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DR EMBL; LGRB01000010; OCT50121.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C1CNR6; -.
DR STRING; 86049.A0A1C1CNR6; -.
DR VEuPathDB; FungiDB:CLCR_06556; -.
DR VEuPathDB; FungiDB:G647_09030; -.
DR eggNOG; KOG0269; Eukaryota.
DR Proteomes; UP000094526; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0032008; P:positive regulation of TOR signaling; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR037590; WDR24.
DR PANTHER; PTHR46200; GATOR COMPLEX PROTEIN WDR24; 1.
DR PANTHER; PTHR46200:SF1; GATOR COMPLEX PROTEIN WDR24; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000094526};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT REPEAT 185..227
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 274..315
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 39..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 690..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 755..812
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 851..895
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 991..1020
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1289..1386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 477..515
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..704
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 851..893
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 998..1014
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1338..1374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1386 AA; 152930 MW; 7FF58890C0B0DE59 CRC64;
MSDPSTSQSQ NLAPPPAPPL PPGRLGQLQR IIAPWGKHIG SKAHGSSAQG ERDGGLGRIG
GIHTYSPHSS RTVTHRTGIP IAALDINKSK THAILAGKEI LKTVRIHDGK ITEDFNLRAS
ISSYASAHIS PHSDSAEKRR EYLPARDVKW SIGNWEHIIA TAATNGRIAL YDLNAPSAKT
EWAWLHEHTG QINKLDIDPH AGYLLLSASQ DKSVRLWDLR APKPDKSRTR FEVRSAVRDV
RWSPVEPFDF AVCADGGFVQ KWDARAPMLP KLSINAHEKA CYSLDYHPDG RHVISGGFDK
YIRVWDFESD KKRQKPVRQL KAPHAIKNIR WRPACSILES EETNLWQSTQ VAVSYHHDDP
RVHIWDLRRP LLPFRELDKY TSPANDLLWA DKDLLWTVGD DGIFTQWDVR HNTPFYNQLA
PCTAQFVPDG RYYSFSEDRE VRHAASHGDS AVGFLSVPRD KLSSGDDGLA SRSLTDDEGG
LESTLGTSSR RRETTTVPSR SNKSQTNSPQ SMDQKPPILS LDEAVLTRPD LFNNDQVGAG
GYVPGVAVEA EVVEYLASHY ATPATVELNR SCPDTILHRL QEAFDQNAAA CDVVGMHRTA
QTWRILGAVV VPELRDWADA NRARRRADAA RRKETLESFR SGARRPALSP LAGLPDRGHN
SHYDSKGYKL ISSLFRGVAE GDRVRAGLDV DSTSNMTTPL AKPLPNSPLT DDKKWAQANI
DDRLDNLPPL PPSVLSSHST AAAAARALMD SSDQAIKSDI SSPKQHKSTE TSKKPATVTG
PPVSPVKRPK SNSLVEQKHA AGPRRSQEDR RAALRDYRAQ ARPILSLGDP VHHGAPASIH
DSAESFPMFS VSTDSSHKVP SVGRSLESAR NAGRTSMQRQ PSDLSSANDD DFDGTYSYRS
LDRAIEDERV NDTFDEPSPS VSAIEPSLQM RFGLDGQTPS SEGQGTWRAP REVKDSWDAS
REHEPILPSQ LGTAVSSSPD IFHFEAGTSV PKPRIHTSNP LRSDHLRHSN SENIRPNESE
LSKTLSLDEL DCPTYLAQDF RPIDLSRYEP KRPFAWSSIP LICQCICFDL ESGIAYAQFS
AHLLMHVHQY FFHPSFCSME ATPGKAVDNL ADRLMTPQFG HRIIGSIFEG HLSFLTQMGL
FESAALLRKV CVELEYLQSY QSSTDGKPAA SGLPDRDHST LSVVCGSCQA PMPAGRNTCE
RCRQARAVCP ICESLEDGYK RGPDTNPAGH TALWGQKNSM WMSCHACGHS GHVRCLREWF
SQHFSQGRCP APGCGCDCGP GLTREHRIER QIKREDEVKL IRGTSPGHNA SGSTKRDPLK
ATPSPAVDKA RAALRNSFAA ERTTQSGDER NLPGRRGSNR GRTSGFSSSR KSVRLVTPGE
EEDGHS
//
