ID   A0A1C1D2R6_9EURO        Unreviewed;      1419 AA.
AC   A0A1C1D2R6;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   RecName: Full=Rap-GAP domain-containing protein {ECO:0000259|PROSITE:PS50085};
GN   ORFNames=CLCR_02714 {ECO:0000313|EMBL:OCT55024.1};
OS   Cladophialophora carrionii.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   Cladophialophora.
OX   NCBI_TaxID=86049 {ECO:0000313|EMBL:OCT55024.1, ECO:0000313|Proteomes:UP000094526};
RN   [1] {ECO:0000313|Proteomes:UP000094526}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KSF {ECO:0000313|Proteomes:UP000094526};
RA   Teixeira M.M., Souza R.C., Almeida L.G., Vicente V.A., de Hoog S.,
RA   Bocca A.L., de Almeida S.R., Vasconcelos A.T., Felipe M.S.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OCT55024.1}.
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DR   EMBL; LGRB01000003; OCT55024.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C1D2R6; -.
DR   STRING; 86049.A0A1C1D2R6; -.
DR   VEuPathDB; FungiDB:CLCR_02714; -.
DR   VEuPathDB; FungiDB:G647_05116; -.
DR   eggNOG; KOG3687; Eukaryota.
DR   Proteomes; UP000094526; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   InterPro; IPR018515; Tuberin-type_domain.
DR   InterPro; IPR027107; Tuberin/Ral-act_asu.
DR   InterPro; IPR024584; Tuberin_N.
DR   PANTHER; PTHR10063; TUBERIN; 1.
DR   PANTHER; PTHR10063:SF0; TUBERIN; 1.
DR   Pfam; PF11864; DUF3384; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   Pfam; PF03542; Tuberin; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094526}.
FT   DOMAIN          1128..1362
FT                   /note="Rap-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50085"
FT   REGION          1..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1358..1419
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        37..54
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1370..1385
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1405..1419
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1419 AA;  158295 MW;  820B5FB67CC47BD4 CRC64;
     MSRDNGSPKE GSAPPNSRDS RRVSLWHLPV ASRSSPSPDG HALSGQTPEK PVSHTTPLQL
     RDVIKEGLSV ATSPEDARAW LVGFGDLNPG TDVSRRFIDL REDHHGDQGT TSLLSLLIQW
     LPTWAQKAGK ARKENKTSRS ASLKDHKNLD WLLQYISDYL ELGHTGFDPQ ELSRTVEAIT
     TLCLNANRQE DIDAGVSILY IISSHFDYPP SGLDQTLVVL CASITSLSEV PRHLFDCAKL
     LATSGLHAGF MSTLYSFVRT PISESPRHYL SHARGATRIL QHLIDERQEG GGFVLSLQDF
     LEVLHPAAQQ GISRFCYDIL NALHAIMSSH RSQTEMPSLD FGMLLETVRL CFEATSPRSQ
     TQDEDRQWEH HSRDRETVSK KLAQDFLRIW DRLPSSDQIA IHELFLHFPH YADQSQLILS
     LNYASANYLS SEDDNIKSQY ADKIYKEIVQ DQALPSAARL RAIEILVQAG NPFNDTMAEP
     STFPHEVYVS IFGGLLDQLD SERDTRVFET LLRSLDHMVS NYEEAAKEKA STIRTIEKIR
     GRLMKDAPAG ESLNDDLAIL ATKVLITIFS YSIHTDADAA VKVFDALVEA ASARCQSRPA
     RLVAKRLLFR IRADDAGFIY IATGSQSRHI ASALVRTRES ADTFKLEIPS QRDSASSTSL
     SARSDAGDPL WMYPETEDVN YPFAGRASRI LNVSKTAYPQ VKEGLDMNIW LMSIIRCLQA
     DQDWETYGYT VVHAGAQLSN IALWLNSIQA IVKLRQVLCE QIVNNSFREP PTSTGLKRSD
     VALCMYDILV NLTPFATMRS EEVQKGFGDD MVRAFISGLG GAWEGTSRGC IHALSLCSLE
     IPSSVATLYP TIIDKMSKNM TQGHLTAHIL EFLIQVALLP EMHSNLNPDE IQMIFGICIQ
     YLEKTRAQQQ STVTAPQGRV SAPSRHSGMN FKRPPYRAAM LTDIGLPQYA AALAYHNILF
     WFLSLRLDLR AKYVQWIVPR LVWKNGRGEE AIDEQGEVLI DMMQRTAFSD LGETSPNHDF
     AGSEDGPVSS ASWIAGLSIV TVEVAGHTGK THITKRQASG TTYAMYQQLT APLPSHHRPG
     HTQIRQQEIT TEVLPPHVML QRVASAAITN LADQPLLLPQ EEYVQRALEG FDRIPTVTSH
     KFGVLFIDEG QTDESEYLPN TGGSADFERL LEGLGYVVSL EPPLQFKPQG LEYPRDGEHT
     IAWRDRVEEI IYFVPTMMPN DVEEDPQCIN KKAHVGNCHV NIIFNRSGLD WDMNNLKSQL
     NYVNIVIRPA CRSREVKDPD FLPGFYWVRV ITRDDLPNIS PAADAKIISA AQLASFVRTL
     ALNASMFCQT WNTKDDDTEF PSAWRARLQQ LKRLKERVMK AADKQAPSGG ATMPSINTPP
     GTSSGRKTPV PREEPGGAKK DGSLASQLDF SSWTIHTRK
//