ID   A0A1C2G3X4_9GAMM        Unreviewed;       248 AA.
AC   A0A1C2G3X4;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=tRNA 2-thiocytidine(32) synthetase TtcA {ECO:0000313|EMBL:OCX46157.1};
GN   ORFNames=A9R16_08260 {ECO:0000313|EMBL:OCX46157.1};
OS   Acidiferrobacter thiooxydans.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Acidiferrobacterales;
OC   Acidiferrobacteraceae; Acidiferrobacter.
OX   NCBI_TaxID=163359 {ECO:0000313|EMBL:OCX46157.1};
RN   [1] {ECO:0000313|EMBL:OCX46157.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ZJ {ECO:0000313|EMBL:OCX46157.1};
RA   Ma L.;
RT   "Draft Genome Sequence of Acidiferrobacter thiooxydans ZJ, a Distinctive
RT   Species of Ectothiorhodospiraceae.";
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OCX46157.1}.
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DR   EMBL; MDCF01000041; OCX46157.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C2G3X4; -.
DR   STRING; 163359.A9R16_08260; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006400; P:tRNA modification; IEA:UniProt.
DR   CDD; cd01993; Alpha_ANH_like_II; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR011063; TilS/TtcA_N.
DR   InterPro; IPR035107; tRNA_thiolation_TtcA_Ctu1.
DR   PANTHER; PTHR43686; SULFURTRANSFERASE-RELATED; 1.
DR   PANTHER; PTHR43686:SF1; TRNA-CYTIDINE(32) 2-SULFURTRANSFERASE; 1.
DR   Pfam; PF01171; ATP_bind_3; 1.
DR   PIRSF; PIRSF004976; ATPase_YdaO; 1.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          29..197
FT                   /note="tRNA(Ile)-lysidine/2-thiocytidine synthase N-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01171"
SQ   SEQUENCE   248 AA;  27583 MW;  7295C1A43179FCBD CRC64;
     MQPIPPRPLL RLTGRAISDY DMIRAGDRVL LAVSGGKDSL GLLQVLRHLQ KKAPLTFDLG
     VATVDPGIDG FDPAPLIPYM ESLGIPYFYE RQAIAARAQA TLGNDSFCSY CARMRRGTLY
     RVARDHGYNV LALAQHLDDI AESFLMSAFH AGTLHTMRAH YRVDAGDLRV IRPFIYVRER
     QLRDFARAAA LPVIPDNCPA CFRKPTERAA MKALLAAEEA RHKDLFRNLL SAVRPLLGAE
     RSPEDGTQ
//