ID A0A1C2GJ48_9SPHI Unreviewed; 1360 AA.
AC A0A1C2GJ48;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BEL04_16145 {ECO:0000313|EMBL:OCX51554.1};
OS Mucilaginibacter sp. PPCGB 2223.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Mucilaginibacter.
OX NCBI_TaxID=1886027 {ECO:0000313|EMBL:OCX51554.1, ECO:0000313|Proteomes:UP000095113};
RN [1] {ECO:0000313|EMBL:OCX51554.1, ECO:0000313|Proteomes:UP000095113}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PPCGB 2223 {ECO:0000313|EMBL:OCX51554.1,
RC ECO:0000313|Proteomes:UP000095113};
RA Seilhamer J.J.;
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCX51554.1}.
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DR EMBL; MDJS01000003; OCX51554.1; -; Genomic_DNA.
DR RefSeq; WP_066005822.1; NZ_MDJS01000003.1.
DR STRING; 1886027.BEL04_16145; -.
DR OrthoDB; 9809670at2; -.
DR Proteomes; UP000095113; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF07494; Reg_prop; 9.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 4.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Kinase {ECO:0000313|EMBL:OCX51554.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000095113};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:OCX51554.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1360
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008661845"
FT TRANSMEM 799..820
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 853..1073
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1114..1229
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1261..1360
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT MOD_RES 1162
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1360 AA; 154333 MW; 2B1ED23BAEF7059B CRC64;
MKKFLLFIIL QLVLISPSFS QLSFDHVSVN NGLSQSTVLT ILKDSRGYMW FGTRDRLNKY
DARNIKTYNY DYRDTTSISC NDYVFFVFED RQKNLWIGTS KGLNRYIPES DSFERILHKD
NDRNSLTTNN IYCTYQDHSG KLWFGSDKGL NMLSSPASRK FTRFFKASPG HPGLSGNQVY
AIYEDREQNL WVGTTEGITR MSLKNGKYIF KTFNSANGLE GNFVQTITQD HEGNICIGTQ
TGGVNIFDPK TATFSHLKHN PSNTNSLINN DIRKIVIDKD DKLWIGTMNG LDIYDQHSRQ
FKLYQHDVEN RNSLSDNSVK DIYFEDNGTV WIGTMFGGVN IIHPNTVPFN IYQASKYKNS
ISGNVVSTII ADAKQNLWIG TEGNGLNYYD KAKLTFTHYT NNPNAEGSIR TNFVKAIYRD
KANNLWVGLH QGGLELLQPS SGTFKHYRHN DADPHSINSD IISCILEDSA NRFWVGTSKG
LDIFDQKQQQ FRTYLNDPSK PLKLSSIGIR CIYEDSGHNI WVGTSGGLNL LKAGTTSFIF
FRANDRDEKS IKAGYINCIR QDNDGNIWVG SFHGGLSRYN PGDGSFKTYQ IKDGLLSDNV
LNIIPADAHD LWISTNNGLT KFNTLTQKFK NYTVADGLPT NEFNYNSSYK DADGILYFGT
YNGLISFDPK QIKENKVTPA VLFTGLKLFN HPVNISDQTG LLQKHISLTK AIIFRSDQNV
FTLDFTALDY DKPGENQFMY KLKGFEKNWN VVDVPSATYT NLPAGDYDFL VKASNADGYW
NNNTTGLHIV ILPPLWRTWW AYTFYVLAFA GSLFLVIRFF RRQARLERDL YYEHLNYERQ
QEVHQMKLDF FTKVSHEIRT PLTLILAPVE KLIDTTLDNP LVSRQLTYVK QNADRLLRLV
NELLDFRKIE TGHLQLHVSE HDLIRFCEDI FSSFERTSIQ KSITYQFKPA IDSLPLYFDP
AQFEKVLFNI LSNAFKFTPD EGTITLSVTA DAQWVNIIIA DNGAGIAAEQ QAHIFENFYQ
ARNNTTSPGW GIGLALVKNI VDQHKGKISV ESELATDAQP GKTVFTISLL KGKAHFDAAD
LDDTPAQSYA IQQAVATPVM ANTESLSPIA EKQSILLVED NNEVRGLIRE SLATSYNIHE
SINGAEGWET ACQLIPDLII SDVTMPVMDG LEFCSKIKTD ERTNHIPVIL LTAKAAYDHQ
VSGLENGADV YITKPFKMQL LELTIRNLMM TRQSMREKFG QQITLMPKNK VIESPDEKFL
NKLMTIVETH MEDSEFDVVK LVNEIGMSQS ILYRKIKALT DLSTGDFIKS VRLKQAALLL
AQQKLSIAEV AYAVGFSDRK YFSKEFKKQF GKTPSEYIEQ
//
