ID A0A1C2GKL8_9SPHI Unreviewed; 659 AA.
AC A0A1C2GKL8;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Histidine kinase domain-containing protein {ECO:0000259|PROSITE:PS50109};
GN ORFNames=BEL04_10975 {ECO:0000313|EMBL:OCX52023.1};
OS Mucilaginibacter sp. PPCGB 2223.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Mucilaginibacter.
OX NCBI_TaxID=1886027 {ECO:0000313|EMBL:OCX52023.1, ECO:0000313|Proteomes:UP000095113};
RN [1] {ECO:0000313|EMBL:OCX52023.1, ECO:0000313|Proteomes:UP000095113}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PPCGB 2223 {ECO:0000313|EMBL:OCX52023.1,
RC ECO:0000313|Proteomes:UP000095113};
RA Seilhamer J.J.;
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCX52023.1}.
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DR EMBL; MDJS01000002; OCX52023.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C2GKL8; -.
DR STRING; 1886027.BEL04_10975; -.
DR OrthoDB; 9778366at2; -.
DR Proteomes; UP000095113; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF65; SENSOR HISTIDINE KINASE COMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF81901; HCP-like; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000095113};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..659
FT /note="Histidine kinase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008661960"
FT TRANSMEM 402..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 563..652
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 659 AA; 75176 MW; 7FC3CC8E80334BA8 CRC64;
MKKYGYLFAI NLICLIPVFR VSAQQFNYNF DSLKRVIQKH PNDPASIHAC VDYAGKFFYT
QSDSAFYYLN KAMALAKRTN NNIGYAYCLK NEGDLYAING ESKKAVMYYK QGLAAFKKSK
ENVLYIKILS NLAITYKNLG ALDSAMQTFD QVSAAFKNNL HTHQDSIALA VHYIQLFDTY
RVQGFKDDAL FYGEKAYTLS KTINYERGIG YGLYVEGLKY YQADPALALK YCNKALDIAV
LKNISELQVF VRSLKADIFI NAGKYRQAEE ELLKDTHYTA GSIRLVTNSK LAKVYYYLKD
YQRALGCYQY AITLAYGLGY RSEIASTLEN GIDIYQKLGN YKTAFVLLKK HEQVQSEMAS
DKLKLDYERS ALKFRAAEKD KQLAQNRLTI EEKDNRLKRQ SLLIMSSIFI IVLLIIVALL
IYHQQKKLQA QRIKNLESAK KIQMLDAAMS GEEKERKRIA ENLHDGIGGL LSAVKMRFSI
FKNEYPELKA SGAYNKAIAM LDDASAEIRK TAHNLMPDML VRFGLDEALQ VFCDNLNQFN
QLKIRYECIG EIGRFNKNVE LMIYRMVQEL INNTIKHSNA KNAYVQLSRQ RNVLSVSIED
DGCGFDKQSL QTAKGMGLNA IEDRINSLGG MLEIDSTLGN GVYIYFELDI LDFNIKSNR
//
