ID   A0A1C2HCG1_9RHOB        Unreviewed;       614 AA.
AC   A0A1C2HCG1;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BFP70_15585 {ECO:0000313|EMBL:OCX61441.1};
OS   Thioclava sp. SK-1.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Thioclava.
OX   NCBI_TaxID=1889770 {ECO:0000313|EMBL:OCX61441.1, ECO:0000313|Proteomes:UP000094269};
RN   [1] {ECO:0000313|EMBL:OCX61441.1, ECO:0000313|Proteomes:UP000094269}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK-1 {ECO:0000313|EMBL:OCX61441.1,
RC   ECO:0000313|Proteomes:UP000094269};
RA   Wong S.-K., Hamasaki K., Yoshizawa S.;
RT   "Draft genome of Thioclava sp. strain SK-1.";
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OCX61441.1}.
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DR   EMBL; MDHA01000067; OCX61441.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C2HCG1; -.
DR   STRING; 1889770.BFP70_15585; -.
DR   OrthoDB; 9814202at2; -.
DR   Proteomes; UP000094269; Unassembled WGS sequence.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF84; SIGNALLING PROTEIN WITH EAL DOMAIN; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000094269}.
FT   DOMAIN          209..343
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          351..608
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   614 AA;  67749 MW;  97FE484324DB49B9 CRC64;
     MKQMMYPIVR DTPDFGSDLA DLLDQLSETA CALCSAQACV IDPAVDLGDM FDTVRTKMQQ
     TADVDPAMAA AIKDMSDELR LTQDAQALRT GVLPRSGGVL RATFGGGLAL YGRCLWSSQG
     EPLGRLTMVF APRDAPKSDQ IHAIDLLTDT IAGALEAFAE RRQLMETLAR SEMQAAALRR
     KSETDPLTRL ENSASFEAKS RQRLTNDAQK YALIVLDIDH FKAINDLYGH KFGDTYLRSM
     AQALRTAVPD SAIIGRLGGD EFGILLELPQ TSGAYLDGLI VRARAAVQRS IAILGKPDIG
     RVSMGVSLFP NHARDFNALF ERADVALYVS KRMGRATSTI FDPHHHDRFN MGVINSRFRK
     ALLQRQIVPF FQPIYDLASG ARAGFEVLSR WDDPQQGILT PDMFPAAFND HLLSEQLTRV
     MIDSALATIT RAQAHQPELA KCDIAVNLTS FDLMNPEFVF DLQSSLSDHE VSWERITLEV
     TERVMLGDRN GQIYRTLSEL RMRGAKVALD DFGTGYGGLR HLDDWPVDVL KIDRYFVQSP
     TSRPHARAVI EAMVSIARAC GFQVVAEGVE TAEQLHLVRD VGCDMAQGFI FSRPVSMAQM
     PQTDGQVDMA GLSA
//