ID A0A1C2IWP4_ACITH Unreviewed; 245 AA.
AC A0A1C2IWP4;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Nitroreductase A {ECO:0000313|EMBL:OCX68958.1};
GN ORFNames=A6P07_17405 {ECO:0000313|EMBL:OCX68958.1};
OS Acidithiobacillus thiooxidans (Thiobacillus thiooxidans).
OC Bacteria; Pseudomonadota; Acidithiobacillia; Acidithiobacillales;
OC Acidithiobacillaceae; Acidithiobacillus.
OX NCBI_TaxID=930 {ECO:0000313|EMBL:OCX68958.1, ECO:0000313|Proteomes:UP000094893};
RN [1] {ECO:0000313|EMBL:OCX68958.1, ECO:0000313|Proteomes:UP000094893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A02 {ECO:0000313|EMBL:OCX68958.1,
RC ECO:0000313|Proteomes:UP000094893};
RA Zhang X., Feng X., Tao J., Ma L., Xiao Y., Liang Y., Liu X., Yin H.;
RT "Comparative genomics of the extreme acidophile Acidithiobacillus
RT thiooxidans reveals intraspecific divergence and niche adaptation.";
RL Int. J. Mol. Sci. 0:0-0(2016).
CC -!- SIMILARITY: Belongs to the flavin oxidoreductase frp family.
CC {ECO:0000256|ARBA:ARBA00008366, ECO:0000256|PIRNR:PIRNR005426}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCX68958.1}.
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DR EMBL; LWSA01000273; OCX68958.1; -; Genomic_DNA.
DR RefSeq; WP_024894513.1; NZ_LZYI01000239.1.
DR AlphaFoldDB; A0A1C2IWP4; -.
DR STRING; 930.GCA_002079865_03039; -.
DR eggNOG; COG0778; Bacteria.
DR Proteomes; UP000094893; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-UniRule.
DR CDD; cd02146; NfsA-like; 1.
DR Gene3D; 3.40.109.10; NADH Oxidase; 1.
DR InterPro; IPR016446; Flavin_OxRdtase_Frp.
DR InterPro; IPR029479; Nitroreductase.
DR InterPro; IPR000415; Nitroreductase-like.
DR PANTHER; PTHR43425; OXYGEN-INSENSITIVE NADPH NITROREDUCTASE; 1.
DR PANTHER; PTHR43425:SF2; OXYGEN-INSENSITIVE NADPH NITROREDUCTASE; 1.
DR Pfam; PF00881; Nitroreductase; 1.
DR PIRSF; PIRSF005426; Frp; 1.
DR SUPFAM; SSF55469; FMN-dependent nitroreductase-like; 1.
PE 3: Inferred from homology;
KW Flavoprotein {ECO:0000256|PIRNR:PIRNR005426};
KW FMN {ECO:0000256|PIRNR:PIRNR005426}; NADP {ECO:0000256|PIRNR:PIRNR005426};
KW Oxidoreductase {ECO:0000256|PIRNR:PIRNR005426}.
FT DOMAIN 8..163
FT /note="Nitroreductase"
FT /evidence="ECO:0000259|Pfam:PF00881"
SQ SEQUENCE 245 AA; 27652 MW; 06561EA4B48FBB1D CRC64;
MNDTLNVLKQ HRSIRRFSGQ PVEQTLVQDI VRCGQHAASS SHIQACTVIQ ISDPHLRDKI
AHLAGDQEYI RSAGAFLVFC ADLHRAARIG SRENQTFVAG MTEHFIIATV DVSLFAQNCV
TAAESMGLGT CYIGAVRNHP QEISDLLHLP EQVYPVFGLC IGYPDQNPDL KPRLPLSVVL
KENSYDETRD EAEISQYDQQ MAEYYRNRNA SQKNSRWTQE IAALVGREAR PHMRGFLERR
GMNTR
//
