ID A0A1C3CWW4_9GAMM Unreviewed; 817 AA.
AC A0A1C3CWW4;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:ODA13231.1};
GN ORFNames=BBP83_07240 {ECO:0000313|EMBL:ODA13231.1};
OS Acinetobacter celticus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=1891224 {ECO:0000313|EMBL:ODA13231.1, ECO:0000313|Proteomes:UP000186553};
RN [1] {ECO:0000313|EMBL:ODA13231.1, ECO:0000313|Proteomes:UP000186553}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ANC 4603 {ECO:0000313|EMBL:ODA13231.1,
RC ECO:0000313|Proteomes:UP000186553};
RA Radolfova-Krizova L., Nemec A.;
RT "Acinetobacter sp. ANC 4603.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODA13231.1}.
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DR EMBL; MBDL01000009; ODA13231.1; -; Genomic_DNA.
DR RefSeq; WP_068887369.1; NZ_MBDL01000009.1.
DR AlphaFoldDB; A0A1C3CWW4; -.
DR STRING; 1891224.BBP83_07240; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000186553; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..498
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 510..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..192
FT /note="DUF4131"
FT /evidence="ECO:0000259|Pfam:PF13567"
FT DOMAIN 247..529
FT /note="ComEC/Rec2-related protein"
FT /evidence="ECO:0000259|Pfam:PF03772"
FT DOMAIN 562..649
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF00753"
SQ SEQUENCE 817 AA; 93634 MW; CD5EDD6C4219C40E CRC64;
MLQWLCLGWI LGIAYMGKMW LNYHITAGWV VFFVLIWLMF ERWIQPYLRQ ISIFATFFTL
IFSLFLGIWL GFGFANNALD QRLSNVVHEP SSQTLIVYIE HLNELSENTI QQKITVLNVP
KNAIENSTVQ YLAYVPKAKE ASEQLKLELG KYYRLNGVLR PAHGYATAGT FDQEKWYVQQ
NISSGFKVNE IEPLTEQQIA ALGYSRVLAS NQALIHQFPL WIEKQRLNFR EFIQRQPLRH
QGLLLALLTG DESLLSKDTK MQFQRFGMSH LLAISGPHVV IFAMMVCWTL QKIIARYRPQ
LYLMIPRQYL LILPFLCCVA MYCVFAGFEI PAVRTLLMCV LGSVILLLQQ KLQPLKLLLF
SASLLLFIDP FSILSAAFWL SYGACFILLR IYQTLQQHQQ ALNTAHTWQK KVWFYLRLLI
ESQWKIFCAL FPLMILFFKQ VSWITPVSNI VAIPWLGLIV VPLDIVAALS FSVSESLSAV
LFQFNDFCLS LLLAFLDGLD ALFEPQLQPI ALNGYMVALL ALLLIIVFMP QGLLPKGWVV
LGVLALLMKD TKPYPFELTI LDVGQGQAIF IRDQQRSIMV DMGGHYNEEK FSVGKQIIQP
FLSVNAVSKL DQLVLTHLDQ DHSGGYFSIK HQLPIQQLYS SEKLDPPAQT KFDYCVQGQR
WQWSKTLSIE VLSPKSEQVK WASQNKNESS CVLYVQLKDG FPYQSFLLMG DAGWQTEFQL
LQDYPNLQVD VLVLGHHGSR HSSAYAFLKA LKPKLVIASA GKFNRYGHPS LITQARLAQL
DIPLITTIQQ GSIQFKQQGN QVHLSYARDH WKWLKRN
//
