ID A0A1C3MXR5_9ACTN Unreviewed; 743 AA.
AC A0A1C3MXR5;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=ABC-type bacteriocin/lantibiotic exporter, contains an N-terminal double-glycine peptidase domain {ECO:0000313|EMBL:SBV25101.1};
GN ORFNames=GA0070620_0570 {ECO:0000313|EMBL:SBV25101.1};
OS Micromonospora krabiensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=307121 {ECO:0000313|EMBL:SBV25101.1, ECO:0000313|Proteomes:UP000199393};
RN [1] {ECO:0000313|Proteomes:UP000199393}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45344 {ECO:0000313|Proteomes:UP000199393};
RA Varghese N.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; LT598496; SBV25101.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C3MXR5; -.
DR STRING; 307121.GA0070620_0570; -.
DR PATRIC; fig|307121.4.peg.585; -.
DR OrthoDB; 9806127at2; -.
DR Proteomes; UP000199393; Chromosome i.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd18779; ABC_6TM_T1SS_like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005074; Peptidase_C39.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR PANTHER; PTHR24221:SF606; COLICIN V SECRETION-PROCESSING ATP-BINDING PROTEIN; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF03412; Peptidase_C39; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS50990; PEPTIDASE_C39; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199393};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..143
FT /note="Peptidase C39"
FT /evidence="ECO:0000259|PROSITE:PS50990"
FT DOMAIN 180..459
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 492..725
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 743 AA; 79247 MW; DC313AA6A3948A73 CRC64;
MGGLTGNGTR RLRPGRRRVP LVLQMADADC GAACLAMIAR WHGVRAPLAA VRERLDIGRD
GVTARALLAA GPRFGLHGRA FRAEPDQVGT LPLPAVAHWE NAHFVVVEHV GERGVRLVDP
ALGRRLLTPD EFAAGFSGTV LTYARDPQSP PEPPAVRSGP IARLRRARPL LRPFLPQLGA
AFTVSLILQA LGLALPMATT VAFDRIMPAR ETALMPYLAL AIAALVLTQF GVAYLRSRLL
VTLQARVDSA LMTRLFGHLL RLPYAFFQQR ASGDLMQRLS SSILLRELVT TQVLTAVIDG
VLVIAYFGVL FASDLAFAGL AAAIGIAQVV AVAVVNGRLL RLGQRHLTVQ ADAESALMEA
LSGIATVKSM GAERQVFDGW LRRYTTALDA DVAQNRLSAT VANITASVQL AGPLALLWLG
TGRLFDGASL GETLGLQALA LSALTPLASL VASAQVLQSV VSHLQRLRDV FAAQPEPAGD
AAQPAPRLTG RISVRDVTFR YDGSAPPVLR GVSFDVAPGE KVAIVGRSGS GKSTLAMLLT
GLYRPTGGEI LFDGVPLSRI DPTALRRQFG VVLQESYLFR DSIRRNVSLV HPGIGMPAIR
AAAEVAAIDE DIAAMPMGYD TQVAERGQAL SGGQRQRLSI ARAVAGQPAV LLLDEATSHL
DVATERRVDQ AISALRCTRI VVAHRLSTVR NADQILVVDG GRVVERGRHE ELLRADGVYA
DLVRCQLTDN SALPGGETWL PVP
//
