ID   A0A1C3N2N2_9ACTN        Unreviewed;       226 AA.
AC   A0A1C3N2N2;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Transcriptional regulator, TetR family {ECO:0000313|EMBL:SBV26834.1};
GN   ORFNames=GA0070620_2331 {ECO:0000313|EMBL:SBV26834.1};
OS   Micromonospora krabiensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=307121 {ECO:0000313|EMBL:SBV26834.1, ECO:0000313|Proteomes:UP000199393};
RN   [1] {ECO:0000313|Proteomes:UP000199393}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45344 {ECO:0000313|Proteomes:UP000199393};
RA   Varghese N.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT598496; SBV26834.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C3N2N2; -.
DR   STRING; 307121.GA0070620_2331; -.
DR   PATRIC; fig|307121.4.peg.2391; -.
DR   Proteomes; UP000199393; Chromosome i.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR   InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR   InterPro; IPR011075; TetR_C.
DR   PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR   PANTHER; PTHR30055:SF246; POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY); 1.
DR   Pfam; PF16859; TetR_C_11; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR   PROSITE; PS01081; HTH_TETR_1; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199393};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          31..91
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50977"
FT   DNA_BIND        54..73
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   226 AA;  24625 MW;  3CA0A274BD765318 CRC64;
     MRYPGRRDVR KEPQVTTEKR RPPAGAAVLR DDITTAIRRA LMRELAAVGY GRLSIEAVAR
     RAGVSKTAIY RRWSSKLDLV LDIVAAAAHG KIPALDTGSL RGDLALLFQV VAHALRHPLA
     SQIIPDLLAE AARNPTIDQT LQQVLRARQQ DIGGRLIRLA VERGELPPDS DPDAAIDLIV
     GPLYWRLAIA RLPLTDSYLD ALVESVVAGL GAQRDVPRPR ARPVAG
//