ID A0A1C3N4B6_9ACTN Unreviewed; 262 AA.
AC A0A1C3N4B6;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=peptide chain release factor N(5)-glutamine methyltransferase {ECO:0000256|ARBA:ARBA00012771};
DE EC=2.1.1.297 {ECO:0000256|ARBA:ARBA00012771};
GN ORFNames=GA0070620_2922 {ECO:0000313|EMBL:SBV27408.1};
OS Micromonospora krabiensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=307121 {ECO:0000313|EMBL:SBV27408.1, ECO:0000313|Proteomes:UP000199393};
RN [1] {ECO:0000313|Proteomes:UP000199393}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45344 {ECO:0000313|Proteomes:UP000199393};
RA Varghese N.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-
CC methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release
CC factor] + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:42896, Rhea:RHEA-
CC COMP:10271, Rhea:RHEA-COMP:10272, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30011, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:61891; EC=2.1.1.297;
CC Evidence={ECO:0000256|ARBA:ARBA00000932};
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DR EMBL; LT598496; SBV27408.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C3N4B6; -.
DR STRING; 307121.GA0070620_2922; -.
DR PATRIC; fig|307121.4.peg.2991; -.
DR OrthoDB; 9800643at2; -.
DR Proteomes; UP000199393; Chromosome i.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004556; HemK-like.
DR InterPro; IPR022446; MeTrfrase_put.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR NCBIfam; TIGR00536; hemK_fam; 1.
DR NCBIfam; TIGR03704; PrmC_rel_meth; 1.
DR PANTHER; PTHR18895; HEMK METHYLTRANSFERASE; 1.
DR PANTHER; PTHR18895:SF74; MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE; 1.
DR Pfam; PF05175; MTS; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:SBV27408.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199393};
KW Transferase {ECO:0000313|EMBL:SBV27408.1}.
FT DOMAIN 81..175
FT /note="Methyltransferase small"
FT /evidence="ECO:0000259|Pfam:PF05175"
SQ SEQUENCE 262 AA; 27463 MW; 243024750968F79D CRC64;
MTVPFTPDRP DLVRRLRAAG CVYAEDEADL LLDAAHSATA LSELVDRRVA GTPLEHLLGW
AEFCGLRVAV DPGVFVPRGR TALLVDAAVA LAGPAPAVVD LCCGSGAAAL VLAHRLAPRW
LAAVDIDPAA VACARRNLAA LEVPVFQGDL FAPLPTRWRG RLDLVIANAP YVPSDAVPLL
PAEARQHEAP VALDGGPDGL AVLRRVIVDA ARWLAPGGHL VVEAAERQTD ALCAELTAAG
LLPTVRHDDD LDATAVTARR PS
//
