ID   A0A1C3P0A9_9ACTN        Unreviewed;       569 AA.
AC   A0A1C3P0A9;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   13-SEP-2023, entry version 20.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|Pfam:PF13676};
GN   ORFNames=FDG2_3694 {ECO:0000313|EMBL:SBW23215.1};
OS   Candidatus Protofrankia californiensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
OC   Protofrankia.
OX   NCBI_TaxID=1839754 {ECO:0000313|EMBL:SBW23215.1, ECO:0000313|Proteomes:UP000199013};
RN   [1] {ECO:0000313|Proteomes:UP000199013}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wibberg D.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FLUV01001548; SBW23215.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C3P0A9; -.
DR   Proteomes; UP000199013; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199013}.
FT   DOMAIN          391..503
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|Pfam:PF13676"
FT   REGION          526..569
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        537..560
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   569 AA;  62456 MW;  E4BB08E9A7AF4924 CRC64;
     MTWNGVREDG VYRQSVPDGV WAWVGVGLAP ITPTAGSGLY SDMSEPRRRA DAFATEMAWI
     AAQRSTAGPL CFDLRYLSDP GSGSLSCAIL GRVFAPDNAR AAHAAVALRE RLAAVPDHVA
     AEPFADTADV RHWLAPIEPH LDGLTEIRKR LTHHYCTRTD TGRRLCFAVS AFTDGDRSWE
     PLWRALARQQ YPTLVSICLE PYMVGDGLRY ALSALAGEYA VLATEIPPRP YKGRVPADTF
     AIEAQPLYAE AVRCYTDHAY RIRVSVASAG PLDPAFGELL AATISPPVRD GAFGGGGPVV
     RRPAPEELQP AWANITTSGR EWLDATYRQG SPPGFLNEPE RILCDLVDVP EAAAAFHLPY
     EVAGDPLLFG IPGRSVVPPP ATTSDDRRWD VALSFAGAQR PYVKRVAAAL RARGVRCFYD
     ADEQIDLWGR YLAEELPVIY AERASVVVVF VSADYAAGDW TNLERRAALN RAVRERREYV
     LPARFDDTAL PGLLSDMVAI DLRAITPERF GMMVADKLGR LEVIASGTAP PTPEMRNGED
     RWQRPNAPRR PHRGTSRSTD IHSRRTPPP
//