ID A0A1C4H5K9_9BIFI Unreviewed; 475 AA.
AC A0A1C4H5K9;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Poly(A) polymerase {ECO:0000313|EMBL:SCC80274.1};
GN ORFNames=GA0061077_1125 {ECO:0000313|EMBL:SCC80274.1};
OS Bifidobacterium commune.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=1505727 {ECO:0000313|EMBL:SCC80274.1, ECO:0000313|Proteomes:UP000242610};
RN [1] {ECO:0000313|Proteomes:UP000242610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R-52791 {ECO:0000313|Proteomes:UP000242610};
RA Varghese N., Submissions Spin;
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; FMBL01000003; SCC80274.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C4H5K9; -.
DR STRING; 1505727.GA0061077_1125; -.
DR OrthoDB; 9805698at2; -.
DR Proteomes; UP000242610; Unassembled WGS sequence.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0031123; P:RNA 3'-end processing; IEA:UniProt.
DR CDD; cd00077; HDc; 1.
DR CDD; cd05398; NT_ClassII-CCAase; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002646; PolA_pol_head_dom.
DR InterPro; IPR032828; PolyA_RNA-bd.
DR InterPro; IPR014065; tRNA_adenylyltransferase.
DR NCBIfam; TIGR00277; HDIG; 1.
DR NCBIfam; TIGR02692; tRNA_CCA_actino; 1.
DR PANTHER; PTHR46173; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR46173:SF1; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF01743; PolyA_pol; 1.
DR Pfam; PF12627; PolyA_pol_RNAbd; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81891; Poly A polymerase C-terminal region-like; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000242610};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 25..153
FT /note="Poly A polymerase head"
FT /evidence="ECO:0000259|Pfam:PF01743"
FT DOMAIN 180..240
FT /note="tRNA nucleotidyltransferase/poly(A) polymerase RNA
FT and SrmB- binding"
FT /evidence="ECO:0000259|Pfam:PF12627"
FT DOMAIN 255..350
FT /note="HD"
FT /evidence="ECO:0000259|Pfam:PF01966"
FT COILED 390..417
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 475 AA; 54126 MW; 09FC791A5475A2D9 CRC64;
MEFEVWPEAI ELGHMFAEQG YELSLVGGPV RDLLLHRKSH DLDFCTSARP EEFEPILKRF
GRDGFWDMGR KFGTLGAMRR RKDGTEVQVE VTTYRSDRYD SDSRKPEVSY GDSLEGDLSR
RDFTVNAMAL RVPDLEFVDP FGGANDLSKG ILRTPVDPRQ SFEDDPLRMM RAVRFVAQLG
FHIEPDTAEA ISDMVDRISI VSAERVRDEV TKLLLSDRPH EGIEALVDSG LADIVLPEIP
ALKLEIDEYH RHKDVFEHTL MVLDRAIALE TGPDGPVPAP DLTLRLASLL HDIGKPGTRR
FEPHGKVSFH HHDAVGAKLV RKRLKALRFD HHVISDVSEL VNLHLRFHGY IDEPWTDSAV
RRYVKDSGHL YERLNRLTRA DATTQNKRKA LMFSEAMDEL EDRVRELKRQ EDFDAIRPDV
NGNEIIEVLG IKPGPEVGRA YKHMLDYRLD HGPADHDTAL AELKRWAADE GLIAE
//
