ID   A0A1C4I4L8_9ACTN        Unreviewed;       442 AA.
AC   A0A1C4I4L8;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Cysteine synthase {ECO:0000313|EMBL:SCD31856.1};
GN   ORFNames=GA0115251_10307 {ECO:0000313|EMBL:SCD31856.1};
OS   Streptomyces sp. TverLS-915.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1839763 {ECO:0000313|EMBL:SCD31856.1, ECO:0000313|Proteomes:UP000198957};
RN   [1] {ECO:0000313|EMBL:SCD31856.1, ECO:0000313|Proteomes:UP000198957}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TverLS-915 {ECO:0000313|EMBL:SCD31856.1,
RC   ECO:0000313|Proteomes:UP000198957};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR   EMBL; FMCE01000024; SCD31856.1; -; Genomic_DNA.
DR   RefSeq; WP_010262695.1; NZ_FMCE01000024.1.
DR   AlphaFoldDB; A0A1C4I4L8; -.
DR   Proteomes; UP000198957; Unassembled WGS sequence.
DR   GO; GO:1901605; P:alpha-amino acid metabolic process; IEA:UniProt.
DR   CDD; cd00158; RHOD; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR   InterPro; IPR001763; Rhodanese-like_dom.
DR   InterPro; IPR036873; Rhodanese-like_dom_sf.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR   Pfam; PF00291; PALP; 1.
DR   Pfam; PF00581; Rhodanese; 1.
DR   SMART; SM00450; RHOD; 1.
DR   SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR   PROSITE; PS50206; RHODANESE_3; 1.
PE   4: Predicted;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198957}.
FT   DOMAIN          350..441
FT                   /note="Rhodanese"
FT                   /evidence="ECO:0000259|PROSITE:PS50206"
SQ   SEQUENCE   442 AA;  47354 MW;  F3ED91460D202C45 CRC64;
     MKYDSILDTI GQTPLVRIDP AVHGLRSTEL YAKLEFFNPF GSVKDRAAWG MARPALADAA
     ERGAEVVELS SGNTAKALAV IASMHGLGFR SVTNRMKIPE VKELLLLLGA EIEELPGQSE
     CLDPTDTEDP LTRFHRELSA PGGSFLHTDQ YFNPANARAH EEGTGPEIIA DLGGRAPDWF
     VAGVGTAGSS SGVARALRAA DGDVRVLGLV AEKSDFVPGI RNLDEVQEVG LFDPATYDLI
     EAVGSLDAID GMVELIRRCG ILAGPTGGAA YHGAVRRLRE VEASEPERRR TAVFVVCDRV
     ESYLSYVRAR RPELLGATAS LATRTAASVG EEERAGVNRM PVAEAQKWLL HEQPLVVDLR
     GPHAYAAQHI EGSVNIADEL FAELLRGGLP FSKSRPVLLA CPVGEKSVGY AAVLTRMGHP
     DVRSLDGGVI AWRDAGAPLV RE
//