ID A0A1C4KTN3_9ACTN Unreviewed; 825 AA.
AC A0A1C4KTN3;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=beta-mannosidase {ECO:0000256|ARBA:ARBA00012754};
DE EC=3.2.1.25 {ECO:0000256|ARBA:ARBA00012754};
GN ORFNames=GA0115251_11694 {ECO:0000313|EMBL:SCD64744.1};
OS Streptomyces sp. TverLS-915.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1839763 {ECO:0000313|EMBL:SCD64744.1, ECO:0000313|Proteomes:UP000198957};
RN [1] {ECO:0000313|EMBL:SCD64744.1, ECO:0000313|Proteomes:UP000198957}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TverLS-915 {ECO:0000313|EMBL:SCD64744.1,
RC ECO:0000313|Proteomes:UP000198957};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-mannose residues
CC in beta-D-mannosides.; EC=3.2.1.25;
CC Evidence={ECO:0000256|ARBA:ARBA00000829};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; FMCE01000156; SCD64744.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C4KTN3; -.
DR Proteomes; UP000198957; Unassembled WGS sequence.
DR GO; GO:0004567; F:beta-mannosidase activity; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR43730; BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43730:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000198957}.
FT DOMAIN 207..306
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT REGION 479..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 825 AA; 90680 MW; 3A81AD912E20619A CRC64;
MKASTPLDHG WTLRLDPRGH RPEQAADALV DEGVPARVPG CAHTDLLAAG LIPDPYLGRN
EEEVAWVGRA DWTYRTTLTG GSGGGHERAD LVFDGLDTVA EVRIGGRVLG RTRNMHRAYR
FDATQALAAG GDVPLEVAFT SAYEEAEAVR ARLGPRPNAY PEPFNFVRKM ASSFGWDWGP
TLVTAGIWRQ ARLERWSLAR LAEVRPEVTV AEDGTGRVRV RIAVERTAGG TARTLRASVR
VAGVEATARL QPGSDAATIC VEVPDVALWW PRGYGEQPLH DCEVTLGTDD TEGAALDSWE
RRVGFRTVAL DTAEDAEGSA FTLRVNGQPV FARGVNWIPD DTLVSRVDAA RYRRRLAQAA
KAGVNLVRVW GGGIYESEDF YDACDEAGLL VWQDFLFACA AYPEEEPLRT EVEAEARENV
VRLMPHPSLV LWNGNNENLW GFRDWGWAEE LNGASWGEGY YLDLLPRVVA EADPTRPYWA
GSPWSGSPER HPNDPRHGTT HSWEVWNRLD YAAYREDVPR FMAEFGWQAP PAYATLRRAL
GENQLAPDSP DMLHHQKAAD GNGKLARGLA PHFGAPVGFD AWHYLTQLNQ ARAVATGIEH
WRAHWPVCAG TVLWQLNDCW PVTSWAAIDG DEREKPLYHE LRRLYADRLL GLTVRDGRLA
LAVVNDAPTP WEGRARVRRL DAKGGEAAAY EPEFTVAERA VGLVELPAAL TELGDPAREF
LVAEADGLRA LHFAVADKEF VSPAGEVRTE VVETAEGADV TVTAHTLVRD LLLQADRLAP
TAKADRGLVT LLPGESVTYR VSGWDGTGAV DAALWWVDKA RSAAG
//
