ID   A0A1C4M2P8_9ACTN        Unreviewed;       488 AA.
AC   A0A1C4M2P8;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:SCD79988.1};
GN   ORFNames=GA0115251_12449 {ECO:0000313|EMBL:SCD79988.1};
OS   Streptomyces sp. TverLS-915.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1839763 {ECO:0000313|EMBL:SCD79988.1, ECO:0000313|Proteomes:UP000198957};
RN   [1] {ECO:0000313|EMBL:SCD79988.1, ECO:0000313|Proteomes:UP000198957}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TverLS-915 {ECO:0000313|EMBL:SCD79988.1,
RC   ECO:0000313|Proteomes:UP000198957};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
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DR   EMBL; FMCE01000227; SCD79988.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C4M2P8; -.
DR   Proteomes; UP000198957; Unassembled WGS sequence.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198957};
KW   Transferase {ECO:0000313|EMBL:SCD79988.1}.
FT   DOMAIN          155..479
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   488 AA;  51118 MW;  3A8FDB8834CC1F65 CRC64;
     MSRYQRRAAF FCLLLLVALV LNAVRVQLVR ASAYDHNPAN RRAAIARWDR PRGDILVGGH
     PVTGSRDTRE QLRYERTYTE GPLYAPVTGF ASQVYGSTLL ERSEDGLLTG TDPGLSAFPL
     WDDLVRARPG GGDVVTTIDP AAQRAAYEGL AGRTGAVAAL DPSTGRVLAL VSSPSYDPGE
     LSGTSRAVTA AWARLTADPA QPLLNRALRQ TYPPGSTFKI VTAAAALDSG TVRDVDEATD
     APDPYRLPGS GTRLANEVEG CGDASLRYAF RWSCNTVFAA LGVRTGLADM VRAAGRFGFG
     EAGPGIPSPV VRSAFGTRLD KAQLALSSIG QYDTRATPLQ MALVASAVAS GGSVPLPRLV
     ERTTTHGGRL VDAPPARTLR QAMTASTAAR LRDLMVDAVE KGTGRRAAIK GATVGGKTGT
     AQHGVGNKGT PYAWFVSWAQ ARDEPSPQVA VAVVVEDASA DRGEISGGGN AAPIARAVMA
     AVVGEKKR
//