ID A0A1C4MC23_9ACTN Unreviewed; 373 AA.
AC A0A1C4MC23;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:SCD83522.1};
GN ORFNames=GA0115251_125549 {ECO:0000313|EMBL:SCD83522.1};
OS Streptomyces sp. TverLS-915.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1839763 {ECO:0000313|EMBL:SCD83522.1, ECO:0000313|Proteomes:UP000198957};
RN [1] {ECO:0000313|EMBL:SCD83522.1, ECO:0000313|Proteomes:UP000198957}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TverLS-915 {ECO:0000313|EMBL:SCD83522.1,
RC ECO:0000313|Proteomes:UP000198957};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FMCE01000238; SCD83522.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C4MC23; -.
DR Proteomes; UP000198957; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06296; PBP1_CatR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000198957};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 45..90
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 373 AA; 40465 MW; 5FEE8EE873FD2431 CRC64;
MEGYERDQTV MRGRDAACSI LRPMRAESPE GTETARAEER GAGRITLAQV GAQAGVSLST
VSKVLNGRPD VAAPTRRKVE ELLEEHGYRR PAPTPPEAPL LEIVFHELDS AWSMELIRGV
QNVANAHGMS VVLTETGTRH SPGADWVEGV LRRRPLGVVL VFSTLPADLK KKLWSRAIPF
VIVDPAGDPE PDVPSVGSAN WAGGLAATRH LIELGHRRTA VITGPEDMLC ALARLDGFRS
AHNMARITPD PELVRFGDFH VSSGHQHALD LLDRPDRPTA IFAGSDLQAL GVLEAARVLG
LRVPHDLSVV GYDNIPLAQW SSPALTTVDQ PLEQMAEEAA RMLLRLRREE EGETRIELGT
RLVVRGSTGV PGV
//
