ID   A0A1C4MFA2_9ACTN        Unreviewed;       940 AA.
AC   A0A1C4MFA2;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=ATP-dependent RNA helicase HelY {ECO:0000313|EMBL:SCD84646.1};
GN   ORFNames=GA0115240_12582 {ECO:0000313|EMBL:SCD84646.1};
OS   Streptomyces sp. DvalAA-14.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1839759 {ECO:0000313|EMBL:SCD84646.1, ECO:0000313|Proteomes:UP000199020};
RN   [1] {ECO:0000313|EMBL:SCD84646.1, ECO:0000313|Proteomes:UP000199020}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DvalAA-14 {ECO:0000313|EMBL:SCD84646.1,
RC   ECO:0000313|Proteomes:UP000199020};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMCH01000241; SCD84646.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C4MFA2; -.
DR   OrthoDB; 3229913at2; -.
DR   Proteomes; UP000199020; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR048392; MTR4-like_stalk.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF21408; MTR4-like_stalk; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:SCD84646.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199020}.
FT   DOMAIN          44..202
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          284..488
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          257..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          651..693
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   940 AA;  104406 MW;  041E07565726BE9A CRC64;
     MTEEMSPAER FAASRRRAAD NATALAQFRE LYEFGLDPFQ IDACQALEAG SGVLVAAPTG
     SGKTIVGEFA VHLALAEGRK CFYTTPIKAL SNQKYNDLAK RYGADKVGLL TGDNSVNGDA
     PVIVMTTEVL RNMLYANSAV LDGLGYVVMD EVHYLSDRFR GAVWEEVIIH LPPSVTLVSL
     SATVSNAEEF GDWLDTVRGD TKVIVSEHRP VPLWQHVMAG RRMYDLFEER AGATDNRGRR
     EVNADLLRLA REENQRTFHP RAKRGREADR ERERRARSRM WTPSRAEVID RLDSEGLLPA
     ITFIFSRAAC EAAVQQCLAA GLRLNNDENR ARVRSIVEER TRAIPDEDLH VLGYFEFLEG
     LERGIAAHHA GMLPTFKEVV EELFVQGLVK AVFATETLAL GINMPARSVV LEKLVKWNGE
     THADITPGEY TQLTGRAGRR GIDIEGHAVV LWQRGFDPGA VAGLAGTRTY PLRSSFKPSY
     NMAVNLVGQF GRHKSRELLE TSFAQFQADR SVVGISKQVQ RNEEGLDGYK GSMTCHLGDF
     DEYMRLRREL KEREAELSRQ GAVHRRAAAS EALEKLKPGD IIHVPAGKYA GLALVLEPGI
     PAGRSTGNRY GEEFHDGPRP LVLTAERQVK RLAQIDFPVP VEALDRMRIP KTFNPRSPQS
     RRDLASAMRS KAGTAGWAAP ARHRKQRSAA ADDNEISRMR AAIRAHPCHG CDEREDHARW
     AERYHRLHRD TQQLERRIEG RTNTIARTFD RVCAVLTELD YLEGDTVTPE GRRLARLYGE
     LDLLASECLR DGVWDGLGPA ELAACASALV YEARNSDDAV APKLPTGNAK EALSEMVRIW
     GRLDALEEDH HISQTEGVGQ REPDLGFAWP AYRWASGHSL DSVLSDADMP AGDFVRWCKQ
     LIDVLGQIGN AAPEHSPVRR NSRRAVDGLL RGVVAYSSVG
//