ID A0A1C4N6T5_9ACTN Unreviewed; 391 AA.
AC A0A1C4N6T5;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:SCD93921.1};
GN ORFNames=GA0115251_130119 {ECO:0000313|EMBL:SCD93921.1};
OS Streptomyces sp. TverLS-915.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1839763 {ECO:0000313|EMBL:SCD93921.1, ECO:0000313|Proteomes:UP000198957};
RN [1] {ECO:0000313|EMBL:SCD93921.1, ECO:0000313|Proteomes:UP000198957}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TverLS-915 {ECO:0000313|EMBL:SCD93921.1,
RC ECO:0000313|Proteomes:UP000198957};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FMCE01000277; SCD93921.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C4N6T5; -.
DR Proteomes; UP000198957; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR039793; UROS/Hem4.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR Pfam; PF02602; HEM4; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000198957}.
FT DOMAIN 296..389
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 296..389
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 391 AA; 41220 MW; 9CB28932020AB268 CRC64;
MGSSGTGQAG AEREAGAERE AGAEREAGPL SGFTVAVTAD RRAEDLLALL RRRGARVLHG
PAMRTVPLED DAELRAVTEE LLAHPPHLVI GTTAVGLRGW FAAAEGWGLG AELSDVLRGA
RLLARGPKVK GALRGAGLTE EWSPASESMA EVLDHLRTFE LRGARVAVQL HGDPLHAFRT
ALAEAGADVL AVPVYRWLPP EDTAPLDRLT DAVLAGTIDA LPFTSAPAAL ALLARAETRG
LRDQLLSALR ESVLVACVGP VTAAPLQALG IPTVAPERFR LAPLVDLLCR ELPSRAREVR
INGHLLTVRG DVALVDGEPR PLPPASAALL RRLADHPGRV VPRAELLRAL PGTGTDPHAV
DAAISRLRTA LATPGLVQTV VKRGYRLAIE P
//
