ID A0A1C4NL23_9ACTN Unreviewed; 558 AA.
AC A0A1C4NL23;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=cellulose synthase (UDP-forming) {ECO:0000256|ARBA:ARBA00012539};
DE EC=2.4.1.12 {ECO:0000256|ARBA:ARBA00012539};
GN ORFNames=GA0115234_1055300 {ECO:0000313|EMBL:SCD98991.1};
OS Streptomyces sp. DvalAA-43.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1839762 {ECO:0000313|EMBL:SCD98991.1, ECO:0000313|Proteomes:UP000199186};
RN [1] {ECO:0000313|EMBL:SCD98991.1, ECO:0000313|Proteomes:UP000199186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DvalAA-43 {ECO:0000313|EMBL:SCD98991.1,
RC ECO:0000313|Proteomes:UP000199186};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FMBW01000043; SCD98991.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C4NL23; -.
DR OrthoDB; 9806824at2; -.
DR Proteomes; UP000199186; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd06421; CESA_CelA_like; 1.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43867; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR PANTHER; PTHR43867:SF2; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Cellulose biosynthesis {ECO:0000256|ARBA:ARBA00022916};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 178..368
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF13632"
SQ SEQUENCE 558 AA; 61695 MW; B2D408BA38777E56 CRC64;
MTIHHLPQPP SDSELYWYFG PQRRWVLISS SFAFVLTAAT MLTFALRTPA LWAFLAVLAL
NVVALTLSSV NSLRQRRLTR RSHEVLVHAW DPPELPSVDL YLPTCGEPLA VLDNAYRAVS
AVDWPGALTV WVLDDAASPE VAGLAASYGY RYVVRPDRGH LKKAGNLNHA LTLSSAEYIA
VLDADFAPRP DFLRHLVPYL ADPGVGIVQS PQCFDTDESM SWIQRAAGSA QEWFFRWIQP
SRDASDAAIC CGSNAVYRRS AIDLADGFAK LDHSEDLFTG LALHEQGFRT LYVPVLVAKG
TSPDNLASFV NQQYRWAMGN LHLMGTPVLK RMRAPWRMRL CFYEGIVGYL TTAVNTFAAP
LPPLVMLFRY PDDVRPWHVL PLLAPLWLWH VLLPRISRSR WRVEVIRANV LTSVAAGAAF
LHTLRGRSAA WVPTGAGGTV KGGMARRVVI VSLAWLCCST GAAVAGLALA VARNGWVPNW
GLALYLLVQC QINLPLIRDL SAELRPARPA SGTARRVRPT GRRLLPRRWP EALAATTLLL
LTALLASGWV NPMLPWLS
//
