ID   A0A1C4QE73_9ACTN        Unreviewed;       681 AA.
AC   A0A1C4QE73;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Rhamnulose-1-phosphate aldolase/alcohol dehydrogenase {ECO:0000313|EMBL:SCE21028.1};
GN   ORFNames=GA0115234_1068129 {ECO:0000313|EMBL:SCE21028.1};
OS   Streptomyces sp. DvalAA-43.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1839762 {ECO:0000313|EMBL:SCE21028.1, ECO:0000313|Proteomes:UP000199186};
RN   [1] {ECO:0000313|EMBL:SCE21028.1, ECO:0000313|Proteomes:UP000199186}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DvalAA-43 {ECO:0000313|EMBL:SCE21028.1,
RC   ECO:0000313|Proteomes:UP000199186};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|ARBA:ARBA00006484}.
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DR   EMBL; FMBW01000054; SCE21028.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C4QE73; -.
DR   OrthoDB; 9774430at2; -.
DR   Proteomes; UP000199186; Unassembled WGS sequence.
DR   CDD; cd08943; R1PA_ADH_SDR_c; 1.
DR   Gene3D; 3.40.225.10; Class II aldolase/adducin N-terminal domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001303; Aldolase_II/adducin_N.
DR   InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR   InterPro; IPR013454; Bifunc_RhaD/ADH.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   NCBIfam; TIGR02632; RhaD_aldol-ADH; 1.
DR   PANTHER; PTHR43669; 5-KETO-D-GLUCONATE 5-REDUCTASE; 1.
DR   PANTHER; PTHR43669:SF8; SHORT-CHAIN TYPE DEHYDROGENASE_REDUCTASE-RELATED; 1.
DR   Pfam; PF13561; adh_short_C2; 1.
DR   Pfam; PF00596; Aldolase_II; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SMART; SM01007; Aldolase_II; 1.
DR   SUPFAM; SSF53639; AraD/HMP-PK domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
FT   DOMAIN          11..213
FT                   /note="Class II aldolase/adducin N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01007"
SQ   SEQUENCE   681 AA;  72494 MW;  AF489F258C47CB42 CRC64;
     MTSATHAEVA ALLARAHRIG ADARNTNYAG GNTSVKATGT DPVTGGDTEL LWVKGSGGDL
     GTLTEAGLAV LRLDRVRALK DVYPGVERED EMVPAFDHCL HGKGGAAPSI DTAMHALVEA
     AHVDHLHPDS GIALACAADG EKLTAECFGD KVAWVGWRRP GFQLGLDIAA VKEASPRAVG
     VILGGHGITA WGETSEECEH NALWMIRTAE AFLHERGRAE PFGPAWAGRE PLPEERRRER
     AAALAPLIRS LASTDRPQVG HFTDTEPVLD FLARTGHPRL ASLGTSCPDH FLRTKVRPLV
     LDLRADAPLD EAAARLRELH GEYREAYRAY YERHASPDSP AMRGADPAIV LVPGVGMFSF
     GKDKQTARVA GEFYLNAIHV MRGAEAVSSY APIEESEKFR IEYWELEEAK LRRMPRPKPL
     ATRVALVTGA GSGIGRAVAQ RLAAEGACVV VADIDAENAA SVAQELGGSD KAVAVTVDVT
     SEEQIVGAFR AAVLAFGGVD LVVNNAGISI SKPLLETTAR DWDLQHDIMA RGSFLVSREA
     ARVMSAQNLG GDIVYITSKN AVFAGPNNIA YSATKADQAH QVRLLAAELG EHGIRVNGIN
     PDGVVRGSGI FAGGWGAQRA ATYGIEEEKL GEFYAQRTLL KREVLPEHVA NAVFALTGGD
     LTHTTGLHVP VDAGVAAAFL R
//