ID   A0A1C4QRK9_9ACTN        Unreviewed;       392 AA.
AC   A0A1C4QRK9;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=RNA cap guanine-N2 methyltransferase {ECO:0000313|EMBL:SCE25290.1};
GN   ORFNames=GA0115242_127018 {ECO:0000313|EMBL:SCE25290.1};
OS   Streptomyces sp. SolWspMP-5a-2.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1838281 {ECO:0000313|EMBL:SCE25290.1, ECO:0000313|Proteomes:UP000199131};
RN   [1] {ECO:0000313|EMBL:SCE25290.1, ECO:0000313|Proteomes:UP000199131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SolWspMP-5a-2 {ECO:0000313|EMBL:SCE25290.1,
RC   ECO:0000313|Proteomes:UP000199131};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMCI01000252; SCE25290.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C4QRK9; -.
DR   OrthoDB; 9810570at2; -.
DR   Proteomes; UP000199131; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR041698; Methyltransf_25.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR041497; Thump-like.
DR   PANTHER; PTHR14741; S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED; 1.
DR   PANTHER; PTHR14741:SF32; TRIMETHYLGUANOSINE SYNTHASE; 1.
DR   Pfam; PF13649; Methyltransf_25; 1.
DR   Pfam; PF18096; Thump_like; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:SCE25290.1};
KW   Transferase {ECO:0000313|EMBL:SCE25290.1}.
FT   DOMAIN          99..165
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13649"
FT   DOMAIN          314..384
FT                   /note="THUMP-like"
FT                   /evidence="ECO:0000259|Pfam:PF18096"
SQ   SEQUENCE   392 AA;  41278 MW;  0CCD1B03FD760D99 CRC64;
     MNDLAPLLTP EGRALLDEVR GTAPADELAV ATRLRRTHPA ALVSAALGQA RLRQRAAAKF
     GEADAGRMFF TPDGVEQSTR ARVAGYRAGR LRALGVTSVA DLCCGIGGDA IALARAGVRV
     LAVDRDPLTA AVARANAQAL GLGHLIEVRE ADVTEVDTSG WDAVFVDPAR RGGRGRIFDP
     EAYSPPLSWA VEAARAAPLA ALKVAPGIPH EAVPGEAEAE WISDGGDVKE AVLWFGTGAG
     TVRATLLPGP RTLVGRGLPD PQVRPVGRWL YEPDGAVVRS HLVAEAAADL DGGLLDPTIA
     YITADEHRPT PFATAYEITD RLPFNLKRLK ALLREREVGT LTVKKRGSAV EPEELRRKVK
     PQGPNAATVF LTRVAGAPTM LIGTPAPPLP GP
//