ID A0A1C4RGH0_9ACTN Unreviewed; 317 AA.
AC A0A1C4RGH0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=2-oxoglutarate dehydrogenase E2 component {ECO:0000313|EMBL:SCE33918.1};
DE Flags: Fragment;
GN ORFNames=GA0115242_13151 {ECO:0000313|EMBL:SCE33918.1};
OS Streptomyces sp. SolWspMP-5a-2.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1838281 {ECO:0000313|EMBL:SCE33918.1, ECO:0000313|Proteomes:UP000199131};
RN [1] {ECO:0000313|EMBL:SCE33918.1, ECO:0000313|Proteomes:UP000199131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SolWspMP-5a-2 {ECO:0000313|EMBL:SCE33918.1,
RC ECO:0000313|Proteomes:UP000199131};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC Evidence={ECO:0000256|ARBA:ARBA00001938};
CC -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00007317}.
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DR EMBL; FMCI01000286; SCE33918.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C4RGH0; -.
DR OrthoDB; 9805770at2; -.
DR Proteomes; UP000199131; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 4.10.320.10; E3-binding domain; 1.
DR InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR InterPro; IPR014276; 2-oxoglutarate_DH_E2.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR036625; E3-bd_dom_sf.
DR InterPro; IPR004167; PSBD.
DR NCBIfam; TIGR02927; SucB_Actino; 1.
DR PANTHER; PTHR43178; DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; 1.
DR PANTHER; PTHR43178:SF5; LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL; 1.
DR Pfam; PF00198; 2-oxoacid_dh; 1.
DR Pfam; PF02817; E3_binding; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
DR SUPFAM; SSF47005; Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex; 1.
DR PROSITE; PS51826; PSBD; 1.
PE 3: Inferred from homology;
FT DOMAIN 13..50
FT /note="Peripheral subunit-binding (PSBD)"
FT /evidence="ECO:0000259|PROSITE:PS51826"
FT REGION 58..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:SCE33918.1"
SQ SEQUENCE 317 AA; 32862 MW; 46F235D58B4AB83D CRC64;
PAPAATSGDD GAYVTPLVRK LAAENGVELG SVKGTGVGGR IRKQDVLAAA EAAKAAAPAP
AAAAPAAKKS APKLEASPLR GQTVKMPRIR KVIGDNMVKA LHEQAQLSSV VEVDVTRLMR
LRGQAKDSFA AREGVKLSPM PFFVKAAAQA LKAHPVINAK INEAEGTITY FDSENVGIAV
DSEKGLMTPV IKHAGDLNIA GIAKATAELA GKVRANKITP DELSGATFTI SNTGSRGALF
DTIIVPPGQV AILGIGATVK RPAVIETEEG TVIGVRDMTY LTLSYDHRLV DGADAARYLT
AVKGILEAGE FEVELGL
//
