ID A0A1C4SEZ4_9ACTN Unreviewed; 367 AA.
AC A0A1C4SEZ4;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=DNA-binding transcriptional regulator, LysR family {ECO:0000313|EMBL:SCE45597.1};
GN ORFNames=GA0115240_16365 {ECO:0000313|EMBL:SCE45597.1};
OS Streptomyces sp. DvalAA-14.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1839759 {ECO:0000313|EMBL:SCE45597.1, ECO:0000313|Proteomes:UP000199020};
RN [1] {ECO:0000313|EMBL:SCE45597.1, ECO:0000313|Proteomes:UP000199020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DvalAA-14 {ECO:0000313|EMBL:SCE45597.1,
RC ECO:0000313|Proteomes:UP000199020};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; FMCH01000561; SCE45597.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C4SEZ4; -.
DR Proteomes; UP000199020; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08414; PBP2_LTTR_aromatics_like; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF0; HCA OPERON TRANSCRIPTIONAL ACTIVATOR HCAR; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000313|EMBL:SCE45597.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199020}.
FT DOMAIN 68..125
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..40
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 367 AA; 39402 MW; D24929EC7F7973C9 CRC64;
MPGRAPLRAR HPDPWIVRPA ALPRQARGDD ELRGGDNLLG MDRDHGGALG PSSPDPNPDP
DPDARREPTT HQLRLFLVLA EELHFGRAAA RLFMTQPALS RQIRALETAL GLQLVQRSSR
SVELTAAGRA LLPDVKAAAD AMARLRGSAG LHQREVAGHL VIGAIGAEAA MPYTRTVLAE
LGIRHPRITV EIRAVNFTEQ IEALMDGELD AAFLRPPLPP RLHTLQLATE ARLACLPADD
PLAARQPITL AQLAGRPVVD VPAGAPRLWW DDWVVNPRPD GTPVRFGPVA ADIEAMLLAV
ARGEAIAFLP AAARQLYPRP GVAYVEVTDL PLSTAALAWL PRNPLPPALA ALLRTARTVV
RRGGATA
//
