ID   A0A1C4T7Y9_9ACTN        Unreviewed;       272 AA.
AC   A0A1C4T7Y9;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Transport permease protein {ECO:0000256|RuleBase:RU361157};
GN   ORFNames=GA0115234_11189 {ECO:0000313|EMBL:SCE55645.1};
OS   Streptomyces sp. DvalAA-43.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1839762 {ECO:0000313|EMBL:SCE55645.1, ECO:0000313|Proteomes:UP000199186};
RN   [1] {ECO:0000313|EMBL:SCE55645.1, ECO:0000313|Proteomes:UP000199186}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DvalAA-43 {ECO:0000313|EMBL:SCE55645.1,
RC   ECO:0000313|Proteomes:UP000199186};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU361157};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU361157}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ABC-2 integral membrane protein family.
CC       {ECO:0000256|RuleBase:RU361157}.
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DR   EMBL; FMBW01000083; SCE55645.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C4T7Y9; -.
DR   OrthoDB; 3214063at2; -.
DR   Proteomes; UP000199186; Unassembled WGS sequence.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   InterPro; IPR013525; ABC2_TM.
DR   InterPro; IPR047817; ABC2_TM_bact-type.
DR   InterPro; IPR000412; ABC_2_transport.
DR   PANTHER; PTHR43027; DOXORUBICIN RESISTANCE ABC TRANSPORTER PERMEASE PROTEIN DRRC-RELATED; 1.
DR   PANTHER; PTHR43027:SF2; TRANSPORT PERMEASE PROTEIN; 1.
DR   Pfam; PF01061; ABC2_membrane; 1.
DR   PIRSF; PIRSF006648; DrrB; 1.
DR   PROSITE; PS51012; ABC_TM2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|RuleBase:RU361157};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361157};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU361157};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU361157}; Transport {ECO:0000256|RuleBase:RU361157}.
FT   TRANSMEM        43..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361157"
FT   TRANSMEM        74..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361157"
FT   TRANSMEM        121..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361157"
FT   TRANSMEM        159..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361157"
FT   TRANSMEM        192..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361157"
FT   TRANSMEM        244..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361157"
FT   DOMAIN          42..265
FT                   /note="ABC transmembrane type-2"
FT                   /evidence="ECO:0000259|PROSITE:PS51012"
SQ   SEQUENCE   272 AA;  28398 MW;  DBE829757FD89914 CRC64;
     MTTSTTTNTG PATTAGRTGT TLLGRLTALG RAEVTLLARN RTAIFVALLM PAAMVLAMKS
     TMKQSVLDGT GLTVAAAALT GGIGIVLIQA VYMNLVSAYV ARREDLVLKR LRTGEVTDRE
     ILIGTALPSV ALALAQTVVI IVAGTAFFGL DAPQRPELLL TGLLLGAVLL TALAAATSVV
     TRTVQTAQLT TLPLFFISMM GSGLFVPLEI MPGPMASVCE LLPATGVMTL VRTGWLGGAE
     GSDLLVAALT GLAWTAFAVF AVQRRFRWDP RR
//