ID A0A1C4TEE3_9ACTN Unreviewed; 494 AA.
AC A0A1C4TEE3;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Transcriptional regulator, GntR family {ECO:0000313|EMBL:SCE57770.1};
GN ORFNames=GA0115234_113311 {ECO:0000313|EMBL:SCE57770.1};
OS Streptomyces sp. DvalAA-43.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1839762 {ECO:0000313|EMBL:SCE57770.1, ECO:0000313|Proteomes:UP000199186};
RN [1] {ECO:0000313|EMBL:SCE57770.1, ECO:0000313|Proteomes:UP000199186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DvalAA-43 {ECO:0000313|EMBL:SCE57770.1,
RC ECO:0000313|Proteomes:UP000199186};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; FMBW01000091; SCE57770.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C4TEE3; -.
DR Proteomes; UP000199186; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 46..114
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT REGION 103..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 494 AA; 52438 MW; 9D32D830E3CF5622 CRC64;
MCEPPEGGKD HLTAIGLRRA MMEGMDRIPP TRLSRLLTGW SRDGTGALPL LLAQALRELA
QRGDVAPGTV LPSQRALATA LGVSRSTVTA AYGLLEAEGR LESRQGSGSR LRGSGGVGEP
ATEGRLASFG TRDGGIDLSS GALDGLPSVA AAVGELSADD LTAALTGDGY LPYGLPDLRE
AIAEYHRSAG LPTSPEQILV TAGSQQAVWL ITQGLVEPGD TVIVEDPTYR GALEALRARG
ARLVPLPADG AHGARALARL SGHVRPRLVY LQPSLHNPTG RGMDEPTRRA WAAVLAEQGL
YTVEDNAYAE LSLHHDAAPV ALAGLLPPAA TATVGTLSKL FWGGLRLGWI RASTPVVRRL
ADIKRSVDLS CPVVDQLLAV RLLRQLPEAR ARRRSRLRAR LAETERLLRD QRTGWRWDRP
DGGSALWVEI PGADAEATAQ LARRAGVLIV PGPAFSAVDG FRHHVRLPFA DHDGGLARAL
PVLVDCAERS RAAH
//
