ID   A0A1C4U3S1_9ACTN        Unreviewed;       198 AA.
AC   A0A1C4U3S1;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Transcriptional regulator, TetR family {ECO:0000313|EMBL:SCE66294.1};
GN   ORFNames=GA0070607_0102 {ECO:0000313|EMBL:SCE66294.1};
OS   Micromonospora coriariae.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=285665 {ECO:0000313|EMBL:SCE66294.1, ECO:0000313|Proteomes:UP000198243};
RN   [1] {ECO:0000313|EMBL:SCE66294.1, ECO:0000313|Proteomes:UP000198243}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44875 {ECO:0000313|EMBL:SCE66294.1,
RC   ECO:0000313|Proteomes:UP000198243};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LT607412; SCE66294.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C4U3S1; -.
DR   OrthoDB; 3869819at2; -.
DR   Proteomes; UP000198243; Chromosome i.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR   Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR   PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR   PANTHER; PTHR30055:SF164; TRANSCRIPTIONAL REPRESSOR MCE3R; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          17..75
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50977"
FT   DNA_BIND        38..57
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   198 AA;  21238 MW;  8468CC2B9820592D CRC64;
     MSEIAGGRRR RRRSDAERSA AAVLDAAVQV LGRHPAATVE QVAAAACVTR QTVYAHYPSR
     PLLVAAVIDR ITAEAVAALD AADVDSGTVT EALLRWLDVT WQLFDRYPLL LHPSVTAIDQ
     ADSDRHHAPV IGRLERLIRR GQATGEFDST LSPAWLVSAT MALGHAAGGE VTAGRMTTAQ
     TAAALRHSIL RVYGVRES
//