ID   A0A1C4UKG5_MICEC        Unreviewed;       498 AA.
AC   A0A1C4UKG5;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Multisubunit sodium/proton antiporter, MrpD subunit {ECO:0000313|EMBL:SCE72168.1};
GN   ORFNames=GA0070618_0419 {ECO:0000313|EMBL:SCE72168.1};
OS   Micromonospora echinospora (Micromonospora purpurea).
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=1877 {ECO:0000313|EMBL:SCE72168.1, ECO:0000313|Proteomes:UP000198253};
RN   [1] {ECO:0000313|EMBL:SCE72168.1, ECO:0000313|Proteomes:UP000198253}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43816 {ECO:0000313|EMBL:SCE72168.1,
RC   ECO:0000313|Proteomes:UP000198253};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU000320}; Multi-
CC       pass membrane protein {ECO:0000256|RuleBase:RU000320}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D
CC       family. {ECO:0000256|ARBA:ARBA00005346}.
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DR   EMBL; LT607413; SCE72168.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C4UKG5; -.
DR   InParanoid; A0A1C4UKG5; -.
DR   OrthoDB; 9768329at2; -.
DR   Proteomes; UP000198253; Chromosome i.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR   InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR   InterPro; IPR001750; ND/Mrp_mem.
DR   PANTHER; PTHR42703:SF1; NA(+)_H(+) ANTIPORTER SUBUNIT D1; 1.
DR   PANTHER; PTHR42703; NADH DEHYDROGENASE; 1.
DR   Pfam; PF00361; Proton_antipo_M; 1.
DR   PRINTS; PR01437; NUOXDRDTASE4.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        31..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        72..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        135..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        206..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        238..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        271..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        299..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        326..347
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        368..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        406..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        446..473
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          129..416
FT                   /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT                   subunit"
FT                   /evidence="ECO:0000259|Pfam:PF00361"
SQ   SEQUENCE   498 AA;  51851 MW;  06E0CE1774C1DA58 CRC64;
     MTALVPLPVV MPLLGAALTL VLPWARAQRA VSVFVLTATL AVSAVLLVRA YADGPLVVRI
     GGWPPPAGIV LVADQLAALM LTVSAAVTLC VLLYSIGQGQ SDLDEGTPVS IFHPTYLVLT
     AGVTNSFLAG DLFNLFVGFE MLLTASYVLI TLGGSDVRIR TGSTYVVVNI LASMIFLSGV
     GLVYAATGTL NLAQLAGRLD TLPADLRLAL QLMLLLAFGI KAAVFPLAAW LPDSYPTAPA
     PVTAVFAGLL TKVGVYAIIR TETLLFPGGR ADALLMVVAG LTMLVGILGA VAQSDLKRLL
     SFTLVSHIGY MIFGVALSTV AGLTGAIFYV LHHITVQTTL FLVAGLIELR AGSTDLRRLG
     GLARITPLIA VLFFVPAMNL AGIPPFPGFL GKLGLFQAGA AVGGALPWTV VAAGAVTSLC
     TLYAASRVWN IAFWRSPRLV GEAPSLPRLM VGSTVALVTL GVTFTLAAGP IFAVTADAAD
     DLYRRTPYVR AVFPEGTP
//