ID A0A1C4VBL9_9ACTN Unreviewed; 778 AA.
AC A0A1C4VBL9;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:SCE81286.1};
GN ORFNames=GA0070607_1882 {ECO:0000313|EMBL:SCE81286.1};
OS Micromonospora coriariae.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=285665 {ECO:0000313|EMBL:SCE81286.1, ECO:0000313|Proteomes:UP000198243};
RN [1] {ECO:0000313|EMBL:SCE81286.1, ECO:0000313|Proteomes:UP000198243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44875 {ECO:0000313|EMBL:SCE81286.1,
RC ECO:0000313|Proteomes:UP000198243};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT607412; SCE81286.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C4VBL9; -.
DR Proteomes; UP000198243; Chromosome i.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 235..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 260..312
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 541..676
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT REGION 687..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 778 AA; 79658 MW; DAE9A3C60A994C09 CRC64;
MTLRGRLTAA FLVVVLGPVL LGAFFVASIV AAVDRSRSTE RLAVAASTVR TSVDALCQQL
RATADAVALT GDPAGTADQL VGRGLAAGVL ITDVTGQVTY ASPGAPSTPW RDCSGPAAPP
GPIRALAARV DLRDRAGTLQ GTVAAAQLVD PAFVARLAAV TGVAVTLLDG GASAGRVTHT
TESREVRDAV LAAASATGGE RVTETSEGRY VRRIGPSSGQ PLPLVLSVAS ERPPALHVTL
VGVVVLAGLL AVLTAWRLAR VTTRPLVELA GAVDRVAHGD LTARVPVRTR DELGRLAAAF
NRMTRETGSY VAALTSSRDQ LRGHLAVLGD TLASTHDLQR ILRVILHSAI AATGARAGAV
LLVEAGGVLV AQCTEGLDGR WPDGDGTETL RVPVGVGVVG AVAATGEPQR GRVEPTEAQA
GEPRCQTYVA VPFATPGGGT TTTTAAPAAP VGGTGEEAGA PAAALGVLAL YDRLGADEFD
DDDLVTLRTF AGHAAVAVDN VRVHEEAQRL SLTDPLTGLW NYRYLRESIR REVERASRFG
RMLSVLALDL DRFKDVNDTY GHAAGDTVLA EFARRVRGEI REVDLAFRQG GEEFVLLLPE
TDARGAAIVA ERLGAAVRET PVAVEAYAGP VVVTVSVGIA VYPDHGSTGR EVLEAADDAL
YAAKAAGRDT YRVAEVCPDV PRREIPVPAG AVSPPDGLPR AGPPVQVARE PGGPARSDPA
AGVPESSSAG PSHARPEPAD GGADSAGDAA RPGPGAGGPG SGGGASSGPH PPRQSRGR
//
