ID   A0A1C4YJF9_MICEC        Unreviewed;      1080 AA.
AC   A0A1C4YJF9;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Acyl-homoserine lactone (AHL) acylase PvdQ {ECO:0000313|EMBL:SCF20786.1};
GN   ORFNames=GA0070618_4042 {ECO:0000313|EMBL:SCF20786.1};
OS   Micromonospora echinospora (Micromonospora purpurea).
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=1877 {ECO:0000313|EMBL:SCF20786.1, ECO:0000313|Proteomes:UP000198253};
RN   [1] {ECO:0000313|EMBL:SCF20786.1, ECO:0000313|Proteomes:UP000198253}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43816 {ECO:0000313|EMBL:SCF20786.1,
RC   ECO:0000313|Proteomes:UP000198253};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S45 family.
CC       {ECO:0000256|ARBA:ARBA00006586}.
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DR   EMBL; LT607413; SCF20786.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C4YJF9; -.
DR   InParanoid; A0A1C4YJF9; -.
DR   OrthoDB; 5240333at2; -.
DR   Proteomes; UP000198253; Chromosome i.
DR   GO; GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:InterPro.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.60.20.10; Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1; 2.
DR   Gene3D; 1.10.439.10; Penicillin Amidohydrolase, domain 1; 1.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR029055; Ntn_hydrolases_N.
DR   InterPro; IPR023343; Penicillin_amidase_dom1.
DR   InterPro; IPR002692; S45.
DR   InterPro; IPR006311; TAT_signal.
DR   PANTHER; PTHR34218:SF4; ACYL-HOMOSERINE LACTONE ACYLASE QUIP; 1.
DR   PANTHER; PTHR34218; PEPTIDASE S45 PENICILLIN AMIDASE; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   Pfam; PF01804; Penicil_amidase; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR   PROSITE; PS50022; FA58C_3; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   3: Inferred from homology;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..34
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           35..1080
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5008709325"
FT   DOMAIN          944..1080
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
FT   REGION          358..379
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1080 AA;  114608 MW;  099036F7696D5467 CRC64;
     MSRPATTRRL LAGATAVVGL AALLVSPAPP PADAAPAVAG KATGTTTFAA NDYCLGECGD
     IVPPGQNGNA TLVEILAHQT LGTMPRHSGD QLGRYADLVY GYAGLRADQI GSFFTDASFG
     VPPTQVERSY SPRADVRIVR DRATGVPHIT GTTRGGTMYG AGYAGAEDRL FTIDLLRHVG
     RGTLTPFAGG APGNRALEQS VWRNSPYTEA DLQAQVDALR SRGPRGAQLY ADVQEYIAGI
     NAYVQDCMDD RNCPGEYVLT GHLDAITNEG GPEPFTMTDL IAIAGVVGGL FGGGGGTEMQ
     SALVRIAARA KYGPTEGDRV WNAFRGQNDP ETVLTLHDGQ SFPYGAADPN AASVALPDAG
     SARPEPVFTD PTGSAGNNTP TPGADLAAAL SGLTISPAHR GMSNAAVVSA AHSATGHPIA
     VFGPQTGYFA PQLLMVQELQ GPGISARGAA FAGLNLYVLL GRGQDYAWSA TSANQDITDT
     YAVPLCTPDG SAPTPTSDHY LFRGQCLPME KLSHVNTWKP TLADGTPAGS YRLVAWRTKL
     GLVAWRGTVG GRPHAFTQLR STYRHEAVSA IGFQMFNDPA LMGSADAFVT SANNVEYAFN
     WFYVNSTESA YLTSGLHPLR AAGSNPNLPM RAEPAYEWQG YDPATNTARY APLATHPQSK
     NQDYYISWNN KQAKDFGAAD GNFSFGAVHR GDLLDKPIKA AIAAGQKFDR ASLTALVQRA
     GLTDLRGVEV LDELIRVLES QPVTDATLAA EISRLKAWRQ DGALRVETAK GSKVYRHAEA
     IRTFDAWWPL LVRGMFAEPL GADLYQALVN TLSINESPSG HQSGDKSTLP GSASTTQLHK
     GSAFQYGWWG WVDKDLRAVL GVPVSGGLGR THCGNGSLAG CRQILLDTLG TAAATPATQT
     YPGDSTCAAG DQWCADAIVQ SPLGGITHAP IAWQNRPTYQ QVVSFPAKRG DDLTNLATQR
     TVTASSSQLG YPAGRAVDGD LGTRWASSRA DDQWLTVDLG SARPVGRVVL AWEEAYARSY
     RIEVSADGST WRTAWSTTTA DGGTDVVTFP TETARYVRMR GLTRATTYGF SLWEMAVYAH
//