ID   A0A1C4ZZN0_MICEC        Unreviewed;       494 AA.
AC   A0A1C4ZZN0;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Fructuronate reductase {ECO:0000313|EMBL:SCF38214.1};
GN   ORFNames=GA0070618_6013 {ECO:0000313|EMBL:SCF38214.1};
OS   Micromonospora echinospora (Micromonospora purpurea).
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=1877 {ECO:0000313|EMBL:SCF38214.1, ECO:0000313|Proteomes:UP000198253};
RN   [1] {ECO:0000313|EMBL:SCF38214.1, ECO:0000313|Proteomes:UP000198253}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43816 {ECO:0000313|EMBL:SCF38214.1,
RC   ECO:0000313|Proteomes:UP000198253};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT607413; SCF38214.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C4ZZN0; -.
DR   InParanoid; A0A1C4ZZN0; -.
DR   OrthoDB; 271711at2; -.
DR   Proteomes; UP000198253; Chromosome i.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0019594; P:mannitol metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR000669; Mannitol_DH.
DR   InterPro; IPR013118; Mannitol_DH_C.
DR   InterPro; IPR023027; Mannitol_DH_CS.
DR   InterPro; IPR013131; Mannitol_DH_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43362:SF1; MANNITOL DEHYDROGENASE 2-RELATED; 1.
DR   PANTHER; PTHR43362; MANNITOL DEHYDROGENASE DSF1-RELATED; 1.
DR   Pfam; PF01232; Mannitol_dh; 1.
DR   Pfam; PF08125; Mannitol_dh_C; 1.
DR   PRINTS; PR00084; MTLDHDRGNASE.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00974; MANNITOL_DHGENASE; 1.
PE   4: Predicted;
FT   DOMAIN          32..191
FT                   /note="Mannitol dehydrogenase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01232"
FT   DOMAIN          223..446
FT                   /note="Mannitol dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08125"
SQ   SEQUENCE   494 AA;  51591 MW;  CC61803F76D7A4D3 CRC64;
     MTVGTGQLGL GALRRLPEAS RPLVRPGTVD VGIVHLGLGA FHRAHQAVYT EAAMARSGGD
     WGIVGVAPRS TGLVTTLAAQ DGLFSVTTTS AEGSHTQVVG ALAGVRHAAS DPAAVVALLA
     DPRVRVVTLT VTEKAYQLDP VSGRLRPDPE VVADLTTDRP PCTVPGLLVR GLLARAAADA
     GPVALVSCDN LPANGRRLRG LVEQSLTYAR VPDRAVAWVA ACVTFPGTMV DRIVPASTEE
     TLAEARRALG VADLAAVAAE PYTQWVIEDV FPGGRPDWGA AGAVLTDDAG SWERLKLRAL
     NGVHSAAAYL GALAGRETIA DALALPHLEP VLRRLVAEDV AASFTPPDRV SVVDYGDQVL
     ARFANPAIRH RAIQVAMDGS QKLPQRVLHT IADLRAAGRD ARWATLVVAA WMRFVRGRAD
     DGTALPLDDP LAERIRAALA AHPDTPAGVT EALFGLTEVF PAELGGDEEV RAAVTGWLTD
     LDRHGVAATL AGAA
//