ID   A0A1C5BIV7_9ACTN        Unreviewed;       552 AA.
AC   A0A1C5BIV7;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Long-chain acyl-CoA synthetase {ECO:0000313|EMBL:SCF58375.1};
GN   ORFNames=GA0115254_105545 {ECO:0000313|EMBL:SCF58375.1};
OS   Streptomyces sp. Ncost-T10-10d.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1839774 {ECO:0000313|EMBL:SCF58375.1, ECO:0000313|Proteomes:UP000198750};
RN   [1] {ECO:0000313|Proteomes:UP000198750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ncost-T10-10d {ECO:0000313|Proteomes:UP000198750};
RA   Varghese N., Submissions Spin;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMDF01000044; SCF58375.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C5BIV7; -.
DR   OrthoDB; 9803968at2; -.
DR   Proteomes; UP000198750; Unassembled WGS sequence.
DR   GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198750}.
FT   DOMAIN          33..417
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          467..542
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   552 AA;  59144 MW;  09A3875B95DBC1C7 CRC64;
     MTESIYAAKP WISLLSEAQR APVDPAETLV HAFRASVARS PGHPALAYFD GRLSYRETDA
     LSDSVAGHLA AEGLERGDRV AIMLQNTPQF VLALLGAWKA GATVVPLNPM YKSGEVGHVL
     KDAEVTALIC ADRAWEAYLR DTAAAAPTVR IALTTSELDL QTQSDERVLG FERLPVPEGA
     DDLVAVARQG LGAPQGRELG SADVALISYT SGTSGTPKGA MNSHGNVMIN AERQRTGHPI
     AEGSSYFALA PLFHITGMVC QLAACLANAG TLVLTYRFHP GVVLEAFTEH RPAYTVGPST
     AFMALAAHPG VTPEHFSSFQ VISSGGAPLP PALVEKFRAG FGPYIRNGYG LTECTAPCAS
     VPPEREAPVD PVSGTLSVGV PGPDTVVRIL DENGSEVPFG EQGEIAVRGP QVVSGYWRLP
     EATAIAFPDG ELRTGDIGFM DSEGWLYVVD RKKDMINASG FKVWPREVED VLYTHPAVRE
     AAVVGVPDAY RGETVRAYVS LRPGATVEPE ELGVYCKERL AAYKYPREVE ILAELPKTAS
     GKILRRELRF PR
//