ID A0A1C5C0Z6_9ACTN Unreviewed; 946 AA.
AC A0A1C5C0Z6;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:SCF64208.1};
GN ORFNames=GA0115259_1005212 {ECO:0000313|EMBL:SCF64208.1};
OS Streptomyces sp. MnatMP-M17.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1839780 {ECO:0000313|EMBL:SCF64208.1, ECO:0000313|Proteomes:UP000198886};
RN [1] {ECO:0000313|EMBL:SCF64208.1, ECO:0000313|Proteomes:UP000198886}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MnatMP-M17 {ECO:0000313|EMBL:SCF64208.1,
RC ECO:0000313|Proteomes:UP000198886};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FMDK01000050; SCF64208.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C5C0Z6; -.
DR Proteomes; UP000198886; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198886};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 351..421
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 506..644
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 653..907
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT REGION 927..946
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 946 AA; 101412 MW; 2850CDB1BB5FAF23 CRC64;
MSAEGMVLGR RSVPGSGSGL LAQLLLALIC GGYATGAALG WGSERLALFM GDFGLSLAAM
IAAVSCFCYA RVRRGPFRPA WLLFSFSSAM ASGGNAVWGW YEVILDEPVP SPSLADLFFL
CFAPPAIVGL LVLAKRPVSR AGWVCLALDS WLIGGSLLTL SWSLALARTT QVRGESVTQA
ALSLAYPLLD IVLVSMVLAL HFRRATGSRS AVNTAIAALA LTVLCDALFT SPLLRETYRS
GQLLDAGWFA GSLLLAYAPW GVRRAPESVP HPRQSRHSRP SGHPIAGSLA AITPYLAAAV
CTLGILYNVI EGRQVDRVVV LTGCTVVLAL VVRQGIMLVD NIALTHELAQ TENHFRSLVQ
GSSDVIMIAA PSGILRYVSP AASGVYGREA EDLVGAELAS IIHPDDLGRV VHEVRRFLAA
PPSEEPTTRI ECRFKSGAGE WLNVESTVNR HQGGLIFNSR DVTERVRLQA QLQHNAEHDP
LTDLPNRALF TERVRQALSG RRTTDPGTAV LFIDLDGFKG VNDRLGHQAG DELLILAAQR
LQDSVRAGDT AARLGGDEFA AIVLGDGSGD QRAREYQVHE IADRLRLKLS QPYRIDGNDV
RVAASIGVAF AEPGITPTDL MRNADLAMYR AKAGGKDRVE LYAPQMQADV VRRTELAARL
RSALHDGEFA LLHQPVVHLA TGRVSSVAAQ ARWRSAQGSL FTPAEFLRVA DDSDRTAELG
RWLLEEAVAQ AAERARTGHA VPVAVRLPAR RLLDRSMPLG SIEALLTRHG LPSGALVIEL
ADTDPRASLD ELEHRLVALR RLGVRIALDG FGSGYAAINA LRRLPVDVLK LDRGLVEGVV
ESARLHKITA GLLRIAGDLG MQSVADGLDV PEQVLALRAM GCTHGQGMAF SGPLDEYRLR
RALVGGAYAL PGGGAVLPVL TGGSLPVRQP RQPVSDRIPR PLDPLK
//
