ID   A0A1C5D5S5_9ACTN        Unreviewed;       497 AA.
AC   A0A1C5D5S5;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN   ORFNames=GA0115254_11692 {ECO:0000313|EMBL:SCF78344.1};
OS   Streptomyces sp. Ncost-T10-10d.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1839774 {ECO:0000313|EMBL:SCF78344.1, ECO:0000313|Proteomes:UP000198750};
RN   [1] {ECO:0000313|Proteomes:UP000198750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ncost-T10-10d {ECO:0000313|Proteomes:UP000198750};
RA   Varghese N., Submissions Spin;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR   EMBL; FMDF01000141; SCF78344.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C5D5S5; -.
DR   Proteomes; UP000198750; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR   PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198750}.
FT   DOMAIN          9..440
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   497 AA;  52556 MW;  813AF5535FA52ED4 CRC64;
     MRGRGAGDGV TAVLGIPYAA APFGARRFRE PQPAPAWDGV RDCTAFGPIA PQSAELPGAP
     VWHPGDEDIL TVNVWVPERA DGGALPVFFW IHGGAYTFGS SAQPDFDGTA LARAGLVVVS
     CNYRVGFEGF GHVSGFPDNR GLLDQVAALC WVRENIAAFG GDSGNVTVAG HSAGGGSVVC
     LMAMEQTRGL FRRAVAHSVP NAFFAAELAV AVSERIAAEA GVAPTAEGLL SVSPEALVAA
     SDKAAAHCAT DPVAAVHTFD PVIFQPVVDG EVLPADPLRV LASGTAREVD LLVCHTLEEY
     WFLHAVGAVR EVTTEAELAD FAEALHLPAH LGDGYCALMP DAPVLDRYLA IFGDAQFGEY
     TTRLAEHHAR AGGRAYLARF ARRREEARPW HTADIPFAFG NLDAVGADFL IGGAPDDHDR
     ALSRRMLRSW AGFAATGDPG WPAVTADTTP VKSWAVPGDH LADDDTSGLR ALWRDVRFDL
     LRPRQATGHH SHGLSGT
//