ID   A0A1C5DJW6_9ACTN        Unreviewed;       768 AA.
AC   A0A1C5DJW6;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=DNA helicase IV {ECO:0000313|EMBL:SCF83201.1};
GN   ORFNames=GA0115259_103316 {ECO:0000313|EMBL:SCF83201.1};
OS   Streptomyces sp. MnatMP-M17.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1839780 {ECO:0000313|EMBL:SCF83201.1, ECO:0000313|Proteomes:UP000198886};
RN   [1] {ECO:0000313|EMBL:SCF83201.1, ECO:0000313|Proteomes:UP000198886}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MnatMP-M17 {ECO:0000313|EMBL:SCF83201.1,
RC   ECO:0000313|Proteomes:UP000198886};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMDK01000322; SCF83201.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C5DJW6; -.
DR   Proteomes; UP000198886; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000198886}.
FT   DOMAIN          200..624
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   REGION          437..463
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         221..228
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   768 AA;  83078 MW;  1A69281F5E8E1596 CRC64;
     MSTRESNDEL RNEQQFISVL YERLDALREQ AEGAVEASIG QVTTVRQARV ERDISVAEQS
     DRLSSLNAVE TGLCFGRIDL QDESGTAETA GIAETAGTGA THHIGRIGMR ADDEEHTPLL
     IDWRAPVARP FYLATGYSPM GLRRRRHITT QGRRVTALHD EIMDLTDTTR TGYEDPDGDA
     VLLSALNSAR TGRMSDIVQT IQAEQDRIIR APHRGVLVVE GGPGTGKTAV ALHRAAYLLY
     AHREQLARRA VLIVGPNPAF LGYIGEVLPS LGETGVLLAT TAELFPGVRA TGTDTPAAAE
     IKGRAAMAEV LAGVVRDRQT VPHRATEIAH DGYGTLLLDR AMAEDARWHA RETGLPHNLA
     RPHFAFHVID ALTNQLAERI GADPLDDGNL LGADDIAQLG KEIATSREVH AAIEELWPLL
     TPQRLIADFL ADPTRLPDGD AELIRRPESG TGSGTDGPWT PADVPLLDEA AELLGADDSA
     ARAAAEAERQ DRIAYAQGVL DLSEGSKTYE FEDQESEVLA AHDIIDAERF ADRQEAADHR
     SAAERAAADR TWAFGHIVVD EAQELSAMAW RLLMRRCPSR SLTLVGDPAQ TGDAAGCDSW
     RQILAPYVGE RWRLARLGVN YRTPVEIMEV AAEVRRTADP LFEPPKSVRS TGRAPLVRTV
     APADLVRTAA ALTDAPELAH PEEGRIAVLA PATLLPALAA ELPHASWGTA PDLTRPVVLL
     SARQAKGLEF DTVIVVDPDG ILKASPRGTN DLYVALTRAT QRLGIVRT
//